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Ginkgo biloba für Cerebrovascular Health

B

Research suggests Ginkgo may help enhance cerebral blood flow through vasodilation. More consistent benefits are observed for vascular-related cognitive symptoms than for general cognitive decline.

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Fazit

Research suggests Ginkgo may help enhance cerebral blood flow through vasodilation. More consistent benefits are observed for vascular-related cognitive symptoms than for general cognitive decline.

Key Study Findings

Review
[Treatment of mild cognitive impairment: value of citicoline].
Dose: None vs.: None Outcome: cognitive function improvement in mild cognitive impairment Wirkung: None None

Population: elderly patients with mild cognitive impairment or chronic brain diseases

Review
Herbal Medicines in Autism Spectrum Disorder: Therapeutic Potential, Plant Components, and Dosage Guidelines.
Dose: None vs.: None Outcome: ASD symptom management Wirkung: None None

Population: Children with autism spectrum disorder

Other
Inhibition of mitochondrial oxidative stress and apoptosis in the protection of Ginkgo biloba extract 50 …
Dose: None vs.: BCAS model mice without GBE50 Outcome: Cognitive impairment and white matter lesions Wirkung: None None

Population: BCAS cerebral small vessel disease mouse model

Meta-Analysis n=22347
Therapeutic strategies in vascular cognitive impairment: A systematic review and meta-analysis.
Dose: None vs.: Various controls Outcome: Cognition and functional outcomes in VCI Wirkung: Ginkgo biloba: Cohen's d 0.83 [0.00-1.67] cognitio None

Population: Patients with vascular cognitive impairment (173 trials)

Other 10 weeks
Ginkgo biloba Extract GBE50 ameliorates cerebrovascular dysfunction and cognitive impairment in a mouse model of …
Dose: None vs.: Untreated APP/PS1 mice Outcome: Cognitive performance in behavioral tests Wirkung: None None

Population: APP/PS1 transgenic Alzheimer's disease mouse model

In Vitro
Ginkgo biloba extract mediates HT22 cell proliferation and migration after oxygen-glucose deprivation/reoxygenation via regulating RhoA-ROCK2 …
Dose: None vs.: OGD/R model vs control in HT22 cells Outcome: Cell proliferation and migration via RhoA-ROCK2 Wirkung: None None

Population: HT22 mouse hippocampal neurons under OGD/R

Key Statistics

12

Studien

2000

Teilnehmer

Positive

B

Bewertung

Referenced Papers

Revista de neurologia None 3 Zitierungen
Acta pharmaceutica Sinica. … 2024 33 Zitierungen
The Senior care … 2021 2 Zitierungen
Biomedicine & pharmacotherapy … 2020 427 Zitierungen
The Practitioner 2010
Prescrire international 2007 2 Zitierungen
Annals of clinical … 2003 47 Zitierungen
American family physician 2003
The Medical clinics … 2002 59 Zitierungen
Archives of physical … 2000 408 Zitierungen
Current opinion in … 1998 30 Zitierungen

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Übliche Dosierungen

general:
120-240 mg/day standardized to 24% flavone glycosides and 6% terpene lactones

Obergrenze: 600 mg/day (doses above show no additional benefit)

In der Forschung untersuchte Dosierungen

Dosierung Dauer Wirkung N
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive 22347
None 10 weeks Positive --
None -- Positive --
None -- Positive --
None -- Positive --

Beste Einnahmezeit: With meals; may require 4-6 weeks for full effects

Safety & Side Effects

Gemeldete Nebenwirkungen

  • Headache
  • Gastrointestinal upset
  • Dizziness
  • Allergic skin reactions (rare)
  • Increased bleeding risk

Bekannte Wechselwirkungen

  • Anticoagulants and antiplatelet drugs (increased bleeding risk)
  • Anticonvulsants (may reduce seizure threshold)
  • SSRIs (serotonin syndrome risk, rare)
  • CYP3A4 substrates (may affect drug metabolism)

Tolerierbare Höchstaufnahmemenge: 600 mg/day (doses above show no additional benefit)

Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.

Frequently Asked Questions

Does Ginkgo biloba help with Cerebrovascular Health?
Based on 12 studies with 2,000 participants, there is moderate evidence from clinical studies that Ginkgo biloba may support Cerebrovascular Health management. Our evidence grade is B (Good Evidence).
How much Ginkgo biloba should I take for Cerebrovascular Health?
Studies have used various dosages. A commonly studied range is 120-240 mg/day standardized to 24% flavone glycosides and 6% terpene lactones. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ginkgo biloba?
Reported side effects may include Headache, Gastrointestinal upset, Dizziness, Allergic skin reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ginkgo biloba and Cerebrovascular Health?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Related Evidence

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