Descripción

Conditioned fear memory testing in 5XFAD Alzheimer's mice demonstrates that treatment with Centella asiatica water extract or its caffeoylquinic acid compounds significantly improved contextual and cued fear responses after 4 weeks of dietary supplementation.

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Source Paper

Caffeoylquinic Acids in Centella asiatica Reverse Cognitive Deficits in Male 5XFAD Alzheimer's Disease Model Mice.

Nutrients (2020)

PMID: 33202902

DOI: 10.3390/nu12113488

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![Figure 5: Conditioned fear memory testing in 5XFAD Alzheimer's mice demonstrates that treatment with Centella asiatica water extract or its caffeoylquinic acid compounds significantly improved contextual and cued fear responses after 4 weeks of dietary supplementation.]()

> Source: Donald G Matthews et al. "Caffeoylquinic Acids in Centella asiatica Reverse Cognitive Deficits in Male 5XF." *Nutrients*, 2020. PMID: [33202902](https://pubmed.ncbi.nlm.nih.gov/33202902/)

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  <img src="" alt="Conditioned fear memory testing in 5XFAD Alzheimer's mice demonstrates that treatment with Centella asiatica water extract or its caffeoylquinic acid compounds significantly improved contextual and cued fear responses after 4 weeks of dietary supplementation." />
  <figcaption>Figure 5. Conditioned fear memory testing in 5XFAD Alzheimer's mice demonstrates that treatment with Centella asiatica water extract or its caffeoylquinic acid compounds significantly improved contextual and cued fear responses after 4 weeks of dietary supplementation.<br>  Source: Donald G Matthews et al. "Caffeoylquinic Acids in Centella asiatica Reverse Cognitive Deficits in Male 5XF." <em>Nutrients</em>, 2020. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/33202902/">33202902</a></figcaption>
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