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Green Tea Extract (EGCG) Oxidative Stress & Neuroinflammation

C

Research suggests EGCG inhibits beta-amyloid aggregation and provides antioxidant neuroprotection. Strong epidemiological data links regular green tea consumption to reduced cognitive decline risk.

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C

結論

Research suggests EGCG inhibits beta-amyloid aggregation and provides antioxidant neuroprotection. Strong epidemiological data links regular green tea consumption to reduced cognitive decline risk.

Key Study Findings

Review
Dietary Antioxidants, Polyphenols, and Vascular Health: Insights From Ultrasound Measurement of Carotid Intima-Media Thickness and …
Dose: None vs: None Outcome: None 効果: None None

対象集団: older adults and individuals with neurodegenerative disorders

Review
Herbal Medicines in Autism Spectrum Disorder: Therapeutic Potential, Plant Components, and Dosage Guidelines.
Dose: None vs: None Outcome: ASD symptom management 効果: None None

対象集団: Children with autism spectrum disorder

Review
Polyphenols and Alzheimer's Disease: A Review on Molecular and Therapeutic Insights With In Silico Support.
Dose: None vs: None Outcome: Neuroprotection in Alzheimer's disease 効果: None None

対象集団: Alzheimer's disease (review with in silico)

Review
Advanced nutraceutical approaches to Parkinson's disease: bridging nutrition and neuroprotection.
Dose: None vs: None Outcome: None 効果: None None

対象集団: None

Other 5 weeks
Mitigating Age-Related Cognitive Decline and Oxidative Status in Rats Treated with Catechin and Polyphenon-60.
Dose: None vs: None Outcome: Cognitive function 効果: None None

対象集団: Rat model

Review
Underlying Mechanisms of Brain Aging and Neurodegenerative Diseases as Potential Targets for Preventive or Therapeutic …
Dose: Various phytochemicals vs: None Outcome: Neuroprotection in aging and neurodegeneration 効果: None None

対象集団: Aging brain and NDD models (review)

Key Statistics

10

研究数

800

参加者数

Positive

C

グレード

Referenced Papers

European journal of … 2020 91 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

general:
250-500 mg/day EGCG
viatea:
3-5 cups/day

上限量: 800 mg/day EGCG from supplements (hepatotoxicity risk above)

研究で検討された用量

用量 期間 効果 N
None -- Positive --
None -- Positive --
None -- Positive --
None -- Mixed --
None 5 weeks Positive --
Various phytochemicals -- Positive --
None -- Positive --
None 8 weeks Positive --

推奨摂取タイミング: Between meals; avoid on empty stomach

Safety & Side Effects

報告されている副作用

  • Liver toxicity at high doses (>800 mg EGCG/day)
  • Insomnia (caffeine content)
  • Gastrointestinal discomfort
  • Iron absorption reduction

既知の相互作用

  • Iron supplements (tannins reduce absorption)
  • Nadolol (reduces blood levels)
  • Blood thinners (mild antiplatelet effect)
  • MAO inhibitors (caffeine interaction)

耐容上限摂取量: 800 mg/day EGCG from supplements (hepatotoxicity risk above)

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does Green Tea Extract (EGCG) help with Oxidative Stress & Neuroinflammation?
Based on 10 studies with 800 participants, there is limited but promising evidence that Green Tea Extract (EGCG) may support Oxidative Stress & Neuroinflammation management. Our evidence grade is C (Some Evidence).
How much Green Tea Extract (EGCG) should I take for Oxidative Stress & Neuroinflammation?
Studies have used various dosages. A commonly studied range is 250-500 mg/day EGCG. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Green Tea Extract (EGCG)?
Reported side effects may include Liver toxicity at high doses (>800 mg EGCG/day), Insomnia (caffeine content), Gastrointestinal discomfort, Iron absorption reduction. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Green Tea Extract (EGCG) and Oxidative Stress & Neuroinflammation?
We rate the evidence as Grade C (Some Evidence). This rating is based on 10 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.

Related Evidence

に関する他の成分: Oxidative Stress & Neuroinflammation

FDAに関する免責事項: これらの記述は米国食品医薬品局(FDA)による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。