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Ginkgo biloba для Cerebrovascular Health

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Research suggests Ginkgo may help enhance cerebral blood flow through vasodilation. More consistent benefits are observed for vascular-related cognitive symptoms than for general cognitive decline.

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Итог

Research suggests Ginkgo may help enhance cerebral blood flow through vasodilation. More consistent benefits are observed for vascular-related cognitive symptoms than for general cognitive decline.

Key Study Findings

Review
[Treatment of mild cognitive impairment: value of citicoline].
Dose: None или: None Outcome: cognitive function improvement in mild cognitive impairment Эффект: None None

Популяция: elderly patients with mild cognitive impairment or chronic brain diseases

Review
Herbal Medicines in Autism Spectrum Disorder: Therapeutic Potential, Plant Components, and Dosage Guidelines.
Dose: None или: None Outcome: ASD symptom management Эффект: None None

Популяция: Children with autism spectrum disorder

Other
Inhibition of mitochondrial oxidative stress and apoptosis in the protection of Ginkgo biloba extract 50 …
Dose: None или: BCAS model mice without GBE50 Outcome: Cognitive impairment and white matter lesions Эффект: None None

Популяция: BCAS cerebral small vessel disease mouse model

Meta-Analysis n=22347
Therapeutic strategies in vascular cognitive impairment: A systematic review and meta-analysis.
Dose: None или: Various controls Outcome: Cognition and functional outcomes in VCI Эффект: Ginkgo biloba: Cohen's d 0.83 [0.00-1.67] cognitio None

Популяция: Patients with vascular cognitive impairment (173 trials)

Other 10 weeks
Ginkgo biloba Extract GBE50 ameliorates cerebrovascular dysfunction and cognitive impairment in a mouse model of …
Dose: None или: Untreated APP/PS1 mice Outcome: Cognitive performance in behavioral tests Эффект: None None

Популяция: APP/PS1 transgenic Alzheimer's disease mouse model

In Vitro
Ginkgo biloba extract mediates HT22 cell proliferation and migration after oxygen-glucose deprivation/reoxygenation via regulating RhoA-ROCK2 …
Dose: None или: OGD/R model vs control in HT22 cells Outcome: Cell proliferation and migration via RhoA-ROCK2 Эффект: None None

Популяция: HT22 mouse hippocampal neurons under OGD/R

Key Statistics

12

Исследования

2000

Участники

Positive

B

Оценка

Referenced Papers

Revista de neurologia None 3 цитирований
Alzheimer's & dementia … 2025 4 цитирований
Acta pharmaceutica Sinica. … 2024 33 цитирований
The Senior care … 2021 2 цитирований
Biomedicine & pharmacotherapy … 2020 427 цитирований
Aging and disease 2017 96 цитирований
Evidence-based complementary and … 2016 19 цитирований
Phytotherapy research : … 2016 13 цитирований
The Practitioner 2010
Prescrire international 2007 2 цитирований
Annals of clinical … 2003 47 цитирований
American family physician 2003
The Medical clinics … 2002 59 цитирований
Archives of physical … 2000 408 цитирований
The Journal of … 2000 39 цитирований
Current opinion in … 1998 30 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

general:
120-240 mg/day standardized to 24% flavone glycosides and 6% terpene lactones

Верхний предел: 600 mg/day (doses above show no additional benefit)

Дозировки, изученные в исследованиях

Дозировка Длительность Эффект N
None -- Positive --
None -- Positive --
None -- Positive --
None -- Positive 22347
None 10 weeks Positive --
None -- Positive --
None -- Positive --
None -- Positive --

Лучшее время приёма: With meals; may require 4-6 weeks for full effects

Safety & Side Effects

Зарегистрированные побочные эффекты

  • Headache
  • Gastrointestinal upset
  • Dizziness
  • Allergic skin reactions (rare)
  • Increased bleeding risk

Известные взаимодействия

  • Anticoagulants and antiplatelet drugs (increased bleeding risk)
  • Anticonvulsants (may reduce seizure threshold)
  • SSRIs (serotonin syndrome risk, rare)
  • CYP3A4 substrates (may affect drug metabolism)

Допустимый верхний уровень потребления: 600 mg/day (doses above show no additional benefit)

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Ginkgo biloba help with Cerebrovascular Health?
Based on 12 studies with 2,000 participants, there is moderate evidence from clinical studies that Ginkgo biloba may support Cerebrovascular Health management. Our evidence grade is B (Good Evidence).
How much Ginkgo biloba should I take for Cerebrovascular Health?
Studies have used various dosages. A commonly studied range is 120-240 mg/day standardized to 24% flavone glycosides and 6% terpene lactones. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ginkgo biloba?
Reported side effects may include Headache, Gastrointestinal upset, Dizziness, Allergic skin reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ginkgo biloba and Cerebrovascular Health?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Related Evidence

Другие ингредиенты для Cerebrovascular Health

Ginkgo biloba для других состояний

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