Ginkgo biloba 用于 Cerebrovascular Health
BResearch suggests Ginkgo may help enhance cerebral blood flow through vasodilation. More consistent benefits are observed for vascular-related cognitive symptoms than for general cognitive decline.
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B
结论
Research suggests Ginkgo may help enhance cerebral blood flow through vasodilation. More consistent benefits are observed for vascular-related cognitive symptoms than for general cognitive decline.
Key Study Findings
Review
[Treatment of mild cognitive impairment: value of citicoline].
Dose: None
vs: None
Outcome: cognitive function improvement in mild cognitive impairment
效果: None
None
研究人群: elderly patients with mild cognitive impairment or chronic brain diseases
Review
Herbal Medicines in Autism Spectrum Disorder: Therapeutic Potential, Plant Components, and Dosage Guidelines.
Dose: None
vs: None
Outcome: ASD symptom management
效果: None
None
研究人群: Children with autism spectrum disorder
Other
Inhibition of mitochondrial oxidative stress and apoptosis in the protection of Ginkgo biloba extract 50 …
Dose: None
vs: BCAS model mice without GBE50
Outcome: Cognitive impairment and white matter lesions
效果: None
None
研究人群: BCAS cerebral small vessel disease mouse model
Meta-Analysis
n=22347
Therapeutic strategies in vascular cognitive impairment: A systematic review and meta-analysis.
Dose: None
vs: Various controls
Outcome: Cognition and functional outcomes in VCI
效果: Ginkgo biloba: Cohen's d 0.83 [0.00-1.67] cognitio
None
研究人群: Patients with vascular cognitive impairment (173 trials)
Other
10 weeks
Ginkgo biloba Extract GBE50 ameliorates cerebrovascular dysfunction and cognitive impairment in a mouse model of …
Dose: None
vs: Untreated APP/PS1 mice
Outcome: Cognitive performance in behavioral tests
效果: None
None
研究人群: APP/PS1 transgenic Alzheimer's disease mouse model
In Vitro
Ginkgo biloba extract mediates HT22 cell proliferation and migration after oxygen-glucose deprivation/reoxygenation via regulating RhoA-ROCK2 …
Dose: None
vs: OGD/R model vs control in HT22 cells
Outcome: Cell proliferation and migration via RhoA-ROCK2
效果: None
None
研究人群: HT22 mouse hippocampal neurons under OGD/R
Key Statistics
12
研究数量
2000
受试者
↑
Positive
B
等级
Referenced Papers
Revista de neurologia
None
3 次引用
Proceedings of the …
2025
8 次引用
Phytomedicine : international …
2025
6 次引用
Journal of ethnopharmacology
2025
5 次引用
Phytomedicine : international …
2025
4 次引用
Therapeutic strategies in vascular cognitive impairment: A systematic review and meta-analysis.
Meta-Analysis
Alzheimer's & dementia …
2025
4 次引用
Frontiers in pharmacology
2025
3 次引用
Nigerian journal of …
2025
2 次引用
Metabolic brain disease
2025
1 次引用
Alternative therapies in …
2025
Degenerative neurological and …
2024
66 次引用
[Not Available].
Review
Acta pharmaceutica Sinica. …
2024
33 次引用
Physiological reports
2024
5 次引用
Pakistan journal of …
2024
2 次引用
Ginkgo biloba GbbZIP08 transcription factor is involved in the regulation of flavonoid biosynthesis.
Other
Journal of plant …
2023
18 次引用
Pharmaceutics
2023
13 次引用
BMJ open
2023
4 次引用
PloS one
2023
Journal of ethnopharmacology
2022
97 次引用
Journal of integrative …
2022
33 次引用
Clinical drug investigation
2022
22 次引用
Journal of ethnopharmacology
2022
17 次引用
Phytomedicine : international …
2022
16 次引用
Gynecological endocrinology : …
2022
6 次引用
Gynecological endocrinology : …
2022
5 次引用
Zhongguo Zhong yao …
2022
2 次引用
Frontiers in cellular …
2021
40 次引用
CNS neuroscience & …
2021
38 次引用
Evidence-based complementary and …
2021
24 次引用
The Senior care …
2021
2 次引用
Biomedicine & pharmacotherapy …
2020
427 次引用
Efficacy and Safety of Ginkgo biloba in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.
Meta-Analysis
The American journal …
2020
24 次引用
Zhongguo Zhong yao …
2020
3 次引用
CNS neuroscience & …
2019
116 次引用
International psychogeriatrics
2018
83 次引用
Aging and disease
2017
96 次引用
ACS chemical biology
2017
78 次引用
Nutrients
2016
53 次引用
Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine.
Review
Evidence-based complementary and …
2016
19 次引用
Effect of Ginkgo Biloba Extract on the Pharmacokinetics and Metabolism of Clopidogrel in Rats.
Other
Phytotherapy research : …
2016
13 次引用
Integrative medicine insights
2015
100 次引用
CNS & neurological …
2015
63 次引用
Proteomics
2015
14 次引用
Sultan Qaboos University …
2012
27 次引用
The Practitioner
2010
Journal of the …
2009
87 次引用
Prescrire international
2007
2 次引用
European neuropsychopharmacology : …
2003
55 次引用
Annals of clinical …
2003
47 次引用
Ginkgo biloba.
Review
American family physician
2003
The Medical clinics …
2002
59 次引用
Alternative therapies in …
2001
Archives of physical …
2000
408 次引用
Life sciences
2000
41 次引用
The Journal of …
2000
39 次引用
Current opinion in …
1998
30 次引用
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 120-240 mg/day standardized to 24% flavone glycosides and 6% terpene lactones
上限： 600 mg/day (doses above show no additional benefit)
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 22347 |
| None | 10 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | -- |
最佳服用时间： With meals; may require 4-6 weeks for full effects
Safety & Side Effects
已报告的副作用
- ⚠ Headache
- ⚠ Gastrointestinal upset
- ⚠ Dizziness
- ⚠ Allergic skin reactions (rare)
- ⚠ Increased bleeding risk
已知相互作用
- ● Anticoagulants and antiplatelet drugs (increased bleeding risk)
- ● Anticonvulsants (may reduce seizure threshold)
- ● SSRIs (serotonin syndrome risk, rare)
- ● CYP3A4 substrates (may affect drug metabolism)
可耐受最高摄入量： 600 mg/day (doses above show no additional benefit)
在开始服用任何补充剂之前，请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Ginkgo biloba help with Cerebrovascular Health?
Based on 12 studies with 2,000 participants, there is moderate evidence from clinical studies that Ginkgo biloba may support Cerebrovascular Health management. Our evidence grade is B (Good Evidence).
How much Ginkgo biloba should I take for Cerebrovascular Health?
Studies have used various dosages. A commonly studied range is 120-240 mg/day standardized to 24% flavone glycosides and 6% terpene lactones. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ginkgo biloba?
Reported side effects may include Headache, Gastrointestinal upset, Dizziness, Allergic skin reactions (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ginkgo biloba and Cerebrovascular Health?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.
Related Evidence
其他成分用于 Cerebrovascular Health
Ginkgo biloba 用于其他健康状况
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