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Creatine لـ Mental Fatigue

B

A systematic review found moderate certainty evidence for positive effects on memory and processing speed. Single-dose supplementation improved cognitive performance during sleep deprivation through ATP replenishment.

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B

الخلاصة

A systematic review found moderate certainty evidence for positive effects on memory and processing speed. Single-dose supplementation improved cognitive performance during sleep deprivation through ATP replenishment.

Key Study Findings

Review
Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: narrative review of creatine supplementation effects on brain function

Other 24 weeks
Analysis of Incidence and Clinical Characteristics of RSV Infection in Hospitalized Children: A Retrospective Study.
Dose: 71.9% مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: rsv infection from january 2019 to december 2020

Randomized Controlled Trial Double-blind
Can Creatine Combat the Mental Fatigue-associated Decrease in Visuomotor Skills?
Dose: 20 g مقابل: placebo Outcome: throughout the protocol التأثير: None P = 0.022

المجتمع المدروس: healthy participants

Review
Beyond sports: Efficacy and safety of creatine supplementation in pathological or paraphysiological conditions of brain …
Dose: 20 g/d مقابل: Placebo Outcome: None التأثير: None None

المجتمع المدروس: elderly

Cohort Study n=480
Decrease in Serum Vitamin D Level of Older Patients with Fatigue.
Dose: None مقابل: Control Outcome: Cognitive function التأثير: None p=0.05

المجتمع المدروس: patients with fatigue and 240 controls without fatigue,

Systematic Review n=281
Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized …
Dose: None مقابل: None Outcome: Cognitive function (memory, intelligence/reasoning) التأثير: None None

المجتمع المدروس: Healthy individuals

Key Statistics

8

الدراسات

600

المشاركون

Positive

B

التقييم

Referenced Papers

Nutrition (Burbank, Los … 2009 85 اقتباسات
Neuroscience research 2002 180 اقتباسات
Pharmacology, biochemistry, and … 1998 60 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

general:
3-5 g/day creatine monohydrate
cognitivesupport:
5 g/day

الحد الأعلى: 5 g/day considered safe for long-term use (ISSN position)

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
None -- Mixed --
71.9% 24 weeks Positive --
20 g -- Positive --
20 g/d -- Positive --
None -- Mixed 480
None -- Positive 281
None -- Positive 16
None -- Positive --

أفضل وقت للتناول: Any time of day; with or without food

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Water retention
  • Mild gastrointestinal discomfort
  • Weight gain (water weight)
  • Muscle cramping (rare, dose-dependent)

التفاعلات المعروفة

  • Nephrotoxic drugs (monitor kidney function with concurrent use)
  • Caffeine (may partially attenuate creatine loading, debated)
  • NSAIDs (theoretical additive kidney stress at high doses)

الحد الأقصى المسموح به: 5 g/day considered safe for long-term use (ISSN position)

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Creatine help with Mental Fatigue?
Based on 8 studies with 600 participants, there is moderate evidence from clinical studies that Creatine may support Mental Fatigue management. Our evidence grade is B (Good Evidence).
How much Creatine should I take for Mental Fatigue?
Studies have used various dosages. A commonly studied range is 3-5 g/day creatine monohydrate. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Creatine?
Reported side effects may include Water retention, Mild gastrointestinal discomfort, Weight gain (water weight), Muscle cramping (rare, dose-dependent). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Creatine and Mental Fatigue?
We rate the evidence as Grade B (Good Evidence). This rating is based on 8 peer-reviewed studies with 600 total participants. The overall direction of effect is positive.

Related Evidence

مكونات أخرى لـ Mental Fatigue

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.