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Integrated model of mitotane's mechanism of action at the mitochondria-associated membranes, summarizing how metabolomic and lipidomic disruptions contribute to its anti-cancer effect in adrenocortical carcinoma.

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![Figure 10: Integrated model of mitotane's mechanism of action at the mitochondria-associated membranes, summarizing how metabolomic and lipidomic disruptions contribute to its anti-cancer effect in adrenocortical carcinoma.]()

> Source: Ségolène Hescot et al. "Identifying mitotane-induced mitochondria-associated membranes dysfunctions: met." *Oncotarget*, 2017. PMID: [29299119](https://pubmed.ncbi.nlm.nih.gov/29299119/)
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  <img src="" alt="Integrated model of mitotane's mechanism of action at the mitochondria-associated membranes, summarizing how metabolomic and lipidomic disruptions contribute to its anti-cancer effect in adrenocortical carcinoma." />
  <figcaption>Figure 10. Integrated model of mitotane's mechanism of action at the mitochondria-associated membranes, summarizing how metabolomic and lipidomic disruptions contribute to its anti-cancer effect in adrenocortical carcinoma.<br>  Source: Ségolène Hescot et al. "Identifying mitotane-induced mitochondria-associated membranes dysfunctions: met." <em>Oncotarget</em>, 2017. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29299119/">29299119</a></figcaption>
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