What is the recommended dosage for Vitamin E?

General: 15 mg/day (RDA); Cognitive Support: 400-800 IU/day

What are the side effects of Vitamin E?

Potential side effects include: Increased bleeding risk at high doses, Nausea and diarrhea, Fatigue and weakness, Blurred vision.

Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage. The brain's high lipid content makes it particularly susceptible to oxidative stress. Research has explored vitamin E's potential role in supporting brain health, primarily through its alpha-tocopherol form.

What dosage of Vitamin E has been used in cognitive studies?

Cognitive studies have used doses ranging from 400 IU to 2,000 IU of alpha-tocopherol daily. Mixed tocopherol formulations including gamma-tocopherol are also available. The tolerable upper intake is 1,000 mg (approximately 1,500 IU) per day. Consult your healthcare provider before high-dose use.

What are the potential side effects of Vitamin E?

High-dose vitamin E supplementation (above 400 IU per day) has been associated with increased bleeding risk in some studies. It may interact with blood-thinning medications and vitamin K. Some meta-analyses have raised concerns about high-dose supplementation. Consult your healthcare provider.

Vitamin E
Vitamin E

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يُعرف أيضاً بـ: Alpha-Tocopherol, D-Alpha-Tocopherol, Mixed Tocopherols, Tocotrienols

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About

Vitamin E is a fat-soluble antioxidant that protects neuronal membranes from lipid peroxidation. High-dose vitamin E may slow functional decline in moderate Alzheimer's disease, though evidence for prevention is mixed.

How It Works

Fat-soluble antioxidant protecting polyunsaturated fatty acids in neuronal membranes; supports mitochondrial membrane integrity; alpha-tocopherol is the primary brain-active form.

Evidence For Conditions

الحالة	التقييم	الدراسات	المشاركون
Age-Related Cognitive Decline	C	12	3000	عرض →

Side Effects

Increased bleeding risk at high doses
Nausea and diarrhea
Fatigue and weakness
Blurred vision

Drug & Supplement Interactions

Anticoagulants (increased bleeding risk)
Statins and niacin (may reduce HDL-raising effects)
Chemotherapy and radiation (may reduce efficacy)

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Related Ingredients

Vitamin D Vitamin B6 Niacin Vitamin B12 Folate

حقائق سريعة

الجرعة: General: 15 mg/day (RDA); Cognitive_Support: 400-800 IU/day
الأشكال الدوائية: softgel capsule liquid
المصادر الطبيعية: Nuts (almonds, hazelnuts), Seeds (sunflower), Vegetable oils, Spinach, Avocado
الحد الأعلى: 1,000 mg/day (1,500 IU natural / 1,100 IU synthetic)
أفضل وقت: With meals containing fat

ملخص الأدلة

Age-Related Cognitive Decline C

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