Skip to main content
BrainCited

Alpha-GPC für Neurotransmitter Imbalance

B

Alpha-GPC provides 40% choline bioavailability, directly supporting acetylcholine synthesis — the primary neurotransmitter for learning and memory. Clinical studies in elderly patients show improvements in cognitive function scores.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'braincited.com'; const params = 'ingredient\u003Dalpha\u002Dgpc\u0026condition\u003Dneurotransmitter\u002Dimbalance'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    


    
    

      Widget powered by
      .
      Free, no account required.
    

  




    








    

        

            B

        

        

            
Fazit

            
            
Alpha-GPC provides 40% choline bioavailability, directly supporting acetylcholine synthesis — the primary neurotransmitter for learning and memory. Clinical studies in elderly patients show improvements in cognitive function scores.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Randomized Controlled Trial
                
                
                
                
            

            
                Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized …
            
            

                
                Dose: None
                
                
                vs.: None
                
                
                Outcome: Cognitive decline
                
                
                Wirkung: None
                
                
                None
                
            

            
            
Population: Alzheimer's disease patients

            
        

        
        

            

                
                    Review
                
                
                
                
            

            
                Choline supplements: An update.
            
            

                
                Dose: alpha-GPC, choline bitartrate, lecithin, citicoline
                
                
                vs.: None
                
                
                Outcome: Cognitive and muscular performance
                
                
                Wirkung: None
                
                
                None
                
            

            
            
Population: General population (review)

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
10

        
Studien

    

    

        
800

        
Teilnehmer

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Bewertung

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
                        
                        
                            
                                RCT
                            
                            
                            
                        
                    

                    

                        Medicine
                        2024
                        
                        3 Zitierungen
                        
                    

                

                
                

                    

                        
                            Choline supplements: An update.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Frontiers in endocrinology
                        2023
                        
                        74 Zitierungen
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Übliche Dosierungen

                

                    
                    

                        
general:

                        
300-600 mg/day

                    

                    
                    

                        
cognitivesupport:

                        
600-1,200 mg/day

                    

                    
                

                
                

                    Obergrenze: Not established; well-tolerated up to 1,200 mg/day
                

                
            

            

            
            

                
In der Forschung untersuchte Dosierungen

                

                    

                        
                            

                                Dosierung
                                Dauer
                                Wirkung
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                            

                                alpha-GPC, choline bitartrate, lecithin, citicoline
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Beste Einnahmezeit: Morning or split dose; with or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Gemeldete Nebenwirkungen

                    
    
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                        
  • 
                            ⚠
                            Insomnia
                        
    • 
                        
                        
  • 
                            ⚠
                            Dizziness
                        
    • 
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Fishy body odor at high doses (TMAO conversion)
                        
    • 
                        
                    

                

                

                
                

                    
Bekannte Wechselwirkungen

                    
    
                        
                        
  • 
                            ●
                            Anticholinergic medications (opposes Alpha-GPC effects)
                        
    • 
                        
                        
  • 
                            ●
                            Cholinesterase inhibitors (additive cholinergic effects)
                        
    • 
                        
                        
  • 
                            ●
                            Scopolamine (opposes cholinergic effects)
                        
    • 
                        
                    

                

                

                
                

                    

                        Tolerierbare Höchstaufnahmemenge: Not established; well-tolerated up to 1,200 mg/day
                    

                

                
            

            

                Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.Konsultieren Sie immer Ihren Arzt, bevor Sie ein Nahrungsergänzungsmittel einnehmen.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Alpha-GPC help with Neurotransmitter Imbalance?
            
        
        

            Based on 10 studies with 800 participants, there is moderate evidence from clinical studies that Alpha-GPC may support Neurotransmitter Imbalance management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Alpha-GPC should I take for Neurotransmitter Imbalance?
            
        
        

            Studies have used various dosages. A commonly studied range is 300-600 mg/day. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Alpha-GPC?
            
        
        

            Reported side effects may include Headache, Insomnia, Dizziness, Gastrointestinal discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Alpha-GPC and Neurotransmitter Imbalance?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 10 peer-reviewed studies with 800 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                

                    
Andere Inhaltsstoffe für Neurotransmitter Imbalance

                    

                        
                        
                            Zinc
                            C

                        
                        
                        
                            Uridine Monophosphate
                            C

                        
                        
                    

                

                

                
                

                    
Alpha-GPC für andere Beschwerden

                    

                        
                        
                            Age-Related Cognitive Decline
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDA-Haftungsausschluss:
        Diese Aussagen wurden nicht von der Food and Drug Administration bewertet. Die Produkte und Informationen auf dieser Website sind nicht dazu bestimmt, Krankheiten zu diagnostizieren, zu behandeln, zu heilen oder zu verhindern. Die dargestellten Evidenzbewertungen basieren auf unserer Analyse veröffentlichter begutachteter Forschung und stellen keine medizinische Beratung dar. Konsultieren Sie immer Ihren Arzt, bevor Sie mit der Einnahme von Nahrungsergänzungsmitteln beginnen.