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Experimental timeline and design of the bile duct ligation mouse model for hepatic encephalopathy, illustrating the surgical procedure, recovery period, and assessment endpoints for brain ammonia, glial activation, and neuroinflammation.
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A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.Cite This Figure
![Figure 1: Experimental timeline and design of the bile duct ligation mouse model for hepatic encephalopathy, illustrating the surgical procedure, recovery period, and assessment endpoints for brain ammonia, glial activation, and neuroinflammation.]() > Source: Wouter Claeys et al. "A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammoni." *Scientific reports*, 2022. PMID: [36266427](https://pubmed.ncbi.nlm.nih.gov/36266427/)
<figure> <img src="" alt="Experimental timeline and design of the bile duct ligation mouse model for hepatic encephalopathy, illustrating the surgical procedure, recovery period, and assessment endpoints for brain ammonia, glial activation, and neuroinflammation." /> <figcaption>Figure 1. Experimental timeline and design of the bile duct ligation mouse model for hepatic encephalopathy, illustrating the surgical procedure, recovery period, and assessment endpoints for brain ammonia, glial activation, and neuroinflammation.<br> Source: Wouter Claeys et al. "A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammoni." <em>Scientific reports</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36266427/">36266427</a></figcaption> </figure>