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Metabolite concentration profiles measured longitudinally in brain tissue of APPswe x PS1de9 transgenic Alzheimer's model mice. The data track neuroinflammatory and metabolic changes associated with disease progression.

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![Figure 45: Metabolite concentration profiles measured longitudinally in brain tissue of APPswe x PS1de9 transgenic Alzheimer's model mice. The data track neuroinflammatory and metabolic changes associated with disease progression.]()

> Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." *Journal of neurochemistry*, 2018. PMID: [29124761](https://pubmed.ncbi.nlm.nih.gov/29124761/)
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  <img src="" alt="Metabolite concentration profiles measured longitudinally in brain tissue of APPswe x PS1de9 transgenic Alzheimer's model mice. The data track neuroinflammatory and metabolic changes associated with disease progression." />
  <figcaption>Figure 45. Metabolite concentration profiles measured longitudinally in brain tissue of APPswe x PS1de9 transgenic Alzheimer's model mice. The data track neuroinflammatory and metabolic changes associated with disease progression.<br>  Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." <em>Journal of neurochemistry</em>, 2018. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29124761/">29124761</a></figcaption>
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