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Tryptophan hydroxylase (TPH) expression in the dorsal raphe nucleus of valerian-treated mice. TPH is the rate-limiting enzyme in serotonin biosynthesis.

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![Figure 407: Tryptophan hydroxylase (TPH) expression in the dorsal raphe nucleus of valerian-treated mice. TPH is the rate-limiting enzyme in serotonin biosynthesis.]()

> Source: Kazim Sahin et al. "Impact of a Novel Valerian Extract on Sleep Quality, Relaxation, and GABA/Seroto." *Antioxidants (Basel, Switzerland)*, 2024. PMID: [38929096](https://pubmed.ncbi.nlm.nih.gov/38929096/)
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  <img src="" alt="Tryptophan hydroxylase (TPH) expression in the dorsal raphe nucleus of valerian-treated mice. TPH is the rate-limiting enzyme in serotonin biosynthesis." />
  <figcaption>Figure 407. Tryptophan hydroxylase (TPH) expression in the dorsal raphe nucleus of valerian-treated mice. TPH is the rate-limiting enzyme in serotonin biosynthesis.<br>  Source: Kazim Sahin et al. "Impact of a Novel Valerian Extract on Sleep Quality, Relaxation, and GABA/Seroto." <em>Antioxidants (Basel, Switzerland)</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/38929096/">38929096</a></figcaption>
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