**Figure 3.** Figure 3. Effects of dapsone (40 mg/kg; ip) on the levels of cytokines IL-1β, IL-17 and IL-4 and BDNF in the prefrontal cortex (PFC) of mice and post-treatment with ALA (25 mg/kg) for 5 consecutive days. (A) Concentration of IL1-β (pg/mL), (B) concentration of IL-4 (pg/mL), (C) concentration of BDNF (pg/mg of protein) and (D) concentration of IL-17 (pg/mL) in the prefrontal cortex by ELISA. Data are presented as mean ± standard deviation (SD). An asterisk (*) indicates a significant effect as determined by two-way repeated measures, ANOVA with Tukey’s test (p < 0.05), in comparison with control group. A pound sign (#) indicates a significant effect in comparison with DDS group (p < 0.05).

Descripción

Cytokine levels (IL-1beta, IL-6, and related markers) in prefrontal cortex tissue of dapsone-treated animals, demonstrating alpha-lipoic acid's anti-inflammatory effects.

More Figures from This Paper

Figure 1

Behavioral or neurological assessment data from a study evaluating alpha-lipoic acid's neuroprotective effects against dapsone-induced neuroinflammation and oxidative stress in an animal model.

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Figure 2

Brain tissue analysis showing markers of neuroinflammation in dapsone-treated animals, comparing alpha-lipoic acid-supplemented versus control groups.

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Figure 4

Histological or immunohistochemical analysis of brain tissue from the alpha-lipoic acid and dapsone neuroinflammation study.

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Figure 5

Antioxidant capacity measurements (TEAC, GSH, SOD, and CAT) in prefrontal cortex tissue, showing alpha-lipoic acid's ability to counteract dapsone-induced oxidative stress.

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Figure 6

Thiobarbituric acid reactive substances (TBARS) measurements indicating lipid peroxidation levels in dapsone-treated animals, with and without alpha-lipoic acid intervention.

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Figure 3

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Source Paper

Alpha-Lipoic Acid Reduces Neuroinflammation and Oxidative Stress Induced by Dapsone in an Animal Model.

Nutrients (2025)

PMID: 40077661

DOI: 10.3390/nu17050791

Cite This Figure

![Figure 3: Cytokine levels (IL-1beta, IL-6, and related markers) in prefrontal cortex tissue of dapsone-treated animals, demonstrating alpha-lipoic acid's anti-inflammatory effects.](https://pdfs.citedhealth.com/figures/40077661/131.png)

> Source: Bruno Alexandre Quadros Gomes et al. "Alpha-Lipoic Acid Reduces Neuroinflammation and Oxidative Stress Induced by Daps." *Nutrients*, 2025. PMID: [40077661](https://pubmed.ncbi.nlm.nih.gov/40077661/)

<figure>
  <img src="https://pdfs.citedhealth.com/figures/40077661/131.png" alt="Cytokine levels (IL-1beta, IL-6, and related markers) in prefrontal cortex tissue of dapsone-treated animals, demonstrating alpha-lipoic acid's anti-inflammatory effects." />
  <figcaption>Figure 3. Cytokine levels (IL-1beta, IL-6, and related markers) in prefrontal cortex tissue of dapsone-treated animals, demonstrating alpha-lipoic acid's anti-inflammatory effects.<br>  Source: Bruno Alexandre Quadros Gomes et al. "Alpha-Lipoic Acid Reduces Neuroinflammation and Oxidative Stress Induced by Daps." <em>Nutrients</em>, 2025. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/40077661/">40077661</a></figcaption>
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Calificación C · 8 estudios