Skip to main content
BrainCited
Fig 4. Results from Morris water maze tests. (A) The average incubation period from the first to fifth day for the four groups. After 3 months and 7 months of intervention, the mice in HG and NG spent much less time searching for new (reversal) hidden pla
Figure 7. Fig 4. Results from Morris water maze tests. (A) The average incubation period from the first to fifth day for the four groups. After 3 months and 7 months of intervention, the mice in HG and NG spent much less time searching for new (reversal) hidden platform on each reversal training day compared to MG, * P<0.001. (B) The time spent in the third quadrant for HG, LG, and NG was much greater than that of the mice in MG, * P<0.01.

Description

Morris water maze test results reveal that nutrient-supplemented APP-PSN mice demonstrate shorter escape latency and improved spatial memory compared to untreated transgenic controls.

More Figures from This Paper

A schematic diagram illustrates the proposed mechanisms by which the compound nutrient mixture may protect against Alzheimer's pathology, including acetylcholine and cAMP signaling.

Figure 4

A schematic diagram illustrates the proposed mechanisms by which the compound nutrient mixture may protect against Alzheimer's pathology, including acetylcholine and cAMP signaling.

diagram
Daily food intake across groups confirms consistent consumption, with no significant differences between the low, high, and model groups during the study.

Figure 5

Daily food intake across groups confirms consistent consumption, with no significant differences between the low, high, and model groups during the study.

chart
Biochemical markers of oxidative stress and antioxidant capacity in brain tissue are compared across treatment groups, showing dose-dependent protective effects.

Figure 6

Biochemical markers of oxidative stress and antioxidant capacity in brain tissue are compared across treatment groups, showing dose-dependent protective effects.

chart
Immunofluorescence staining of amyloid-beta plaques in the temporal cortex and hippocampus shows reduced plaque burden in nutrient-treated APP-PSN transgenic mice.

Figure 8

Immunofluorescence staining of amyloid-beta plaques in the temporal cortex and hippocampus shows reduced plaque burden in nutrient-treated APP-PSN transgenic mice.

micrograph

Figure 7

Chart
786 × 501px · 173,3 Kio

Source Paper

Protective Effects of Dietary Supplementation with a Combination of Nutrients in a Transgenic Mouse Model of Alzheimer's Disease.

PloS one (2015)

PMID: 26606074

DOI: 10.1371/journal.pone.0143135

Cite This Figure

![Figure 7: Morris water maze test results reveal that nutrient-supplemented APP-PSN mice demonstrate shorter escape latency and improved spatial memory compared to untreated transgenic controls.](https://pdfs.citedhealth.com/figures/26606074/220.png)

> Source: Shengyuan Wang et al. "Protective Effects of Dietary Supplementation with a Combination of Nutrients in." *PloS one*, 2015. PMID: [26606074](https://pubmed.ncbi.nlm.nih.gov/26606074/)
<figure>
  <img src="https://pdfs.citedhealth.com/figures/26606074/220.png" alt="Morris water maze test results reveal that nutrient-supplemented APP-PSN mice demonstrate shorter escape latency and improved spatial memory compared to untreated transgenic controls." />
  <figcaption>Figure 7. Morris water maze test results reveal that nutrient-supplemented APP-PSN mice demonstrate shorter escape latency and improved spatial memory compared to untreated transgenic controls.<br>  Source: Shengyuan Wang et al. "Protective Effects of Dietary Supplementation with a Combination of Nutrients in." <em>PloS one</em>, 2015. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/26606074/">26606074</a></figcaption>
</figure>

Preuves associées

A
Omega-3 Fatty Acids (DHA/EPA) pour Age-Related Cognitive Decline

Note A · 58 études

 B
Phosphatidylserine pour Age-Related Cognitive Decline

Note B · 16 études