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Magnesium L-Threonate per Memory Loss

B

The only magnesium form demonstrated to cross the blood-brain barrier effectively. A 30-day RCT using Magtein PS showed significant improvements across all five subcategories of clinical memory testing and overall memory quotient scores.

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            B

        

        

            
In sintesi

            
            
The only magnesium form demonstrated to cross the blood-brain barrier effectively. A 30-day RCT using Magtein PS showed significant improvements across all five subcategories of clinical memory testing and overall memory quotient scores.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Review
                
                
                
                
            

            
                Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Age-related memory decline via NR2B upregulation
                
                
                Effetto: None
                
                
                None
                
            

            
            
Popolazione: Elderly with age-related memory decline

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
6

        
Studi

    

    

        
450

        
Partecipanti

    

    

        
            
            ↑
            
        
        
Positive

    

    

        B

        
Grado

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        Expert opinion on …
                        2014
                        
                        55 citazioni
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
1,500-2,000 mg/day (providing ~144 mg elemental magnesium)

                    

                    
                    

                        
cognitivesupport:

                        
2,000 mg/day

                    

                    
                

                
                

                    Limite massimo: 350 mg/day elemental magnesium from supplements (IOM)
                

                
            

            

            
            

                
Dosaggi studiati nella ricerca

                

                    

                        
                            

                                Dosaggio
                                Durata
                                Effetto
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Momento migliore per l'assunzione: Evening preferred (may support sleep quality); split into 2-3 doses
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Drowsiness
                        
    • 
                        
                        
  • 
                            ⚠
                            Headache
                        
    • 
                        
                        
  • 
                            ⚠
                            Gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild diarrhea
                        
    • 
                        
                    

                

                

                
                

                    
Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Antibiotics (quinolones, tetracyclines — reduced absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Bisphosphonates (reduced absorption)
                        
    • 
                        
                        
  • 
                            ●
                            Diuretics (may affect magnesium levels)
                        
    • 
                        
                        
  • 
                            ●
                            Muscle relaxants (additive sedation)
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: 350 mg/day elemental magnesium from supplements (IOM)
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Magnesium L-Threonate help with Memory Loss?
            
        
        

            Based on 6 studies with 450 participants, there is moderate evidence from clinical studies that Magnesium L-Threonate may support Memory Loss management. Our evidence grade is B (Good Evidence).
        

    

    
    

        
            How much Magnesium L-Threonate should I take for Memory Loss?
            
        
        

            Studies have used various dosages. A commonly studied range is 1,500-2,000 mg/day (providing ~144 mg elemental magnesium). Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Magnesium L-Threonate?
            
        
        

            Reported side effects may include Drowsiness, Headache, Gastrointestinal discomfort, Mild diarrhea. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Magnesium L-Threonate and Memory Loss?
            
        
        

            We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 450 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Magnesium L-Threonate per altre condizioni

                    

                        
                        
                            Sleep-Related Cognitive Impairment
                            C

                        
                        
                    

                

                
            

        

        

    


    
    












    

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        Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.