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Schematic of calcium homeostasis disruption in aging neurons, depicting how mitochondrial calcium overload contributes to synaptic dysfunction and eventual neuronal death in Alzheimer's disease pathology.
Figure 15
DiagramSource Paper
Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence.Cite This Figure
![Figure 15: Schematic of calcium homeostasis disruption in aging neurons, depicting how mitochondrial calcium overload contributes to synaptic dysfunction and eventual neuronal death in Alzheimer's disease pathology.]() > Source: Imane Lejri et al. "Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Rel." *Oxidative medicine and cellular longevity*, 2019. PMID: [31214285](https://pubmed.ncbi.nlm.nih.gov/31214285/)
<figure> <img src="" alt="Schematic of calcium homeostasis disruption in aging neurons, depicting how mitochondrial calcium overload contributes to synaptic dysfunction and eventual neuronal death in Alzheimer's disease pathology." /> <figcaption>Figure 15. Schematic of calcium homeostasis disruption in aging neurons, depicting how mitochondrial calcium overload contributes to synaptic dysfunction and eventual neuronal death in Alzheimer's disease pathology.<br> Source: Imane Lejri et al. "Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Rel." <em>Oxidative medicine and cellular longevity</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/31214285/">31214285</a></figcaption> </figure>