Descrizione
Thrombosis analysis in MTHFR-deficient models with and without SIRT1 activation, demonstrating the impact of this intervention on clot formation. Reduced thrombotic tendency suggests SIRT1 may counteract prothrombotic pathways linked to MTHFR polymorphism.
Figure 3
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SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency.Cite This Figure
![Figure 3: Thrombosis analysis in MTHFR-deficient models with and without SIRT1 activation, demonstrating the impact of this intervention on clot formation. Reduced thrombotic tendency suggests SIRT1 may counteract prothrombotic pathways linked to MTHFR polymorphism.]() > Source: Albino Carrizzo et al. "SIRT1 pharmacological activation rescues vascular dysfunction and prevents throm." *Cellular and molecular life sciences : CMLS*, 2022. PMID: [35821533](https://pubmed.ncbi.nlm.nih.gov/35821533/)
<figure> <img src="" alt="Thrombosis analysis in MTHFR-deficient models with and without SIRT1 activation, demonstrating the impact of this intervention on clot formation. Reduced thrombotic tendency suggests SIRT1 may counteract prothrombotic pathways linked to MTHFR polymorphism." /> <figcaption>Figure 3. Thrombosis analysis in MTHFR-deficient models with and without SIRT1 activation, demonstrating the impact of this intervention on clot formation. Reduced thrombotic tendency suggests SIRT1 may counteract prothrombotic pathways linked to MTHFR polymorphism.<br> Source: Albino Carrizzo et al. "SIRT1 pharmacological activation rescues vascular dysfunction and prevents throm." <em>Cellular and molecular life sciences : CMLS</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35821533/">35821533</a></figcaption> </figure>