What is the recommended dosage for Vitamin D?

General: 600-2,000 IU/day; Deficiency Correction: 4,000-5,000 IU/day

What are the side effects of Vitamin D?

Potential side effects include: Hypercalcemia at very high doses, Nausea and vomiting, Kidney stones (rare, high doses), Weakness and fatigue.

Vitamin D is a fat-soluble vitamin and neurosteroid hormone that plays a role in brain development and function. Vitamin D receptors are widely distributed throughout the brain. Research has associated low vitamin D status with increased risk of cognitive concerns, particularly in older adults.

What dosage of Vitamin D has been used in cognitive studies?

Cognitive studies have used 800 IU to 4,000 IU of vitamin D3 (cholecalciferol) daily. Some studies have targeted specific serum 25(OH)D levels, typically above 30 ng/mL. The tolerable upper intake is 4,000 IU per day for adults. Consult your healthcare provider and consider testing your levels.

What are the potential side effects of Vitamin D?

Vitamin D toxicity is rare but can occur with prolonged intake above 10,000 IU per day, causing hypercalcemia with symptoms including nausea, weakness, and kidney problems. Vitamin D may interact with certain heart and kidney medications. Consult your healthcare provider for appropriate dosing.

Vitamin D
Vitamin D

vitamin

Noto anche come: Vitamin D3, Cholecalciferol, Calciferol, Ergocalciferol (D2)

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About

Vitamin D is a neurosteroid hormone with receptors throughout the brain, particularly in the hippocampus and cerebral cortex. Deficiency, which affects 40% of geriatric memory clinic patients, is identified as a critical risk factor for cognitive decline. Supplementation supports calcium signaling in neurons, neurotrophic factor expression, and protection against oxidative stress and inflammation.

How It Works

Neurosteroid hormone with receptors in the hippocampus and cerebral cortex; supports calcium signaling in neurons, neurotrophic factor expression, neurotransmitter synthesis, and neuronal protection against oxidative stress and inflammation.

Evidence For Conditions

Condizione	Grado	Studi	Partecipanti
Nutritional Deficiency Cognitive Impairment	B	20	4500	Visualizza →
Depression-Related Cognitive Dysfunction	C	12	2000	Visualizza →

Side Effects

Hypercalcemia at very high doses
Nausea and vomiting
Kidney stones (rare, high doses)
Weakness and fatigue

Drug & Supplement Interactions

Corticosteroids (reduce calcium absorption)
Statins (both affect cholesterol pathways)
Thiazide diuretics (additive calcium retention)
Weight loss drugs (may reduce vitamin D absorption)

Informare sempre il proprio medico di tutti gli integratori che si assumono.Informate sempre il vostro medico di tutti gli integratori che assumete.

Related Ingredients

Vitamin B6 Vitamin E Niacin Vitamin B12 Folate

Informazioni rapide

Dosaggio: General: 600-2,000 IU/day; Deficiency_Correction: 4,000-5,000 IU/day
Forme: softgel capsule tablet drops gummy
Fonti naturali: Sunlight, Fatty fish, Fortified milk, Egg yolks, Mushrooms
Limite massimo: 4,000 IU/day (IOM); 10,000 IU/day (Endocrine Society upper safety)
Momento migliore: With meals containing fat; morning preferred

Riepilogo delle evidenze

Nutritional Deficiency Cognitive Impairment B

Depression-Related Cognitive Dysfunction C

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.