Uridine Monophosphate 관련 Neurotransmitter Imbalance
CThe uridine + DHA + choline combination (known as the 'Mr. Happy Stack') provides synergistic support for phospholipid synthesis and dopamine receptor expression. Limited but promising clinical evidence.
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C
결론
The uridine + DHA + choline combination (known as the 'Mr. Happy Stack') provides synergistic support for phospholipid synthesis and dopamine receptor expression. Limited but promising clinical evidence.
Key Study Findings
Observational Study
Combining Metabolomics and Proteomics to Reveal Key Serum Compounds Related to Canine Intervertebral Disc Herniation.
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: Dogs with intervertebral disc herniation
In Vitro
The Effects of Semen Ziziphi Spinosae Extract on LPS-Induced Astrocyte Gene Expression and Metabolites.
Dose: None
vs: LPS-treated astrocyte controls
Outcome: Astrocyte gene expression and metabolite changes
효과: None
None
대상 집단: LPS-induced inflammatory astrocyte model
Review
Involvement of uridine in brain and gut health: insights into its neuroprotective potential via the …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: None
Other
1H and 31P magnetic resonance spectroscopy reveals potential pathogenic and biomarker metabolite alterations in Lafora …
Dose: None
vs: None
Outcome: None
효과: None
P = 0.013
대상 집단: Healthy adults
Other
4 weeks
Jujuboside A Regulates Calcium Homeostasis and Structural Plasticity to Alleviate Depression-Like Behavior via Shh Signaling …
Dose: 5 mg/kg
vs: None
Outcome: Cognitive function
효과: None
None
대상 집단: Sprague Dawley rats
In Vitro
Integrated Analysis of Transcriptomics and Metabolomics Unveil the Novel Insight of One-Year-Old Precocious Mechanism in …
Dose: 1 g
vs: None
Outcome: None
효과: None
None
대상 집단: None
Key Statistics
4
연구
300
참여자
↑
Positive
C
등급
Referenced Papers
Metabolites
2025
Nutrients
2025
Pharmacological reports : …
2025
Drug design, development …
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8 인용
Brain communications
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International journal of …
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12 인용
Aging and disease
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9 인용
EMBO reports
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5 인용
International journal of …
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4 인용
Neurochemistry international
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12 인용
Autonomic neuroscience : …
2021
9 인용
Metabolites
2020
29 인용
Clinical pharmacokinetics
2018
128 인용
American journal of …
2017
14 인용
European journal of …
2017
9 인용
Neurobiology of disease
2016
83 인용
Autonomic neuroscience : …
2015
81 인용
Physiology & behavior
2015
45 인용
BMC pediatrics
2015
15 인용
PloS one
2011
62 인용
European journal of …
2011
16 인용
Stem cell research
2010
18 인용
Experimental neurology
2009
170 인용
Annual review of …
2009
141 인용
Alzheimer's & dementia …
2008
96 인용
FASEB journal : …
2008
95 인용
Journal of neurochemistry
2008
91 인용
Biotechnology and applied …
2008
7 인용
The European journal …
2007
55 인용
Expression of the homeodomain transcription factor Meis2 in the embryonic and postnatal retina.
Other
The Journal of …
2007
36 인용
Journal of molecular …
2005
66 인용
Drug news & …
2005
43 인용
Neuropsychopharmacology : official …
2005
39 인용
Journal of neuroendocrinology
2002
83 인용
Journal of neuroscience …
2002
58 인용
The Biochemical journal
2002
43 인용
Journal of neurophysiology
2002
27 인용
Is there a role for uridine and pyrimidine nucleosides in the treatment of vascular dementia?
Review
Functional neurology
2002
Journal of neuroscience …
2001
76 인용
Hormones and behavior
2001
45 인용
The Journal of …
2000
745 인용
The Journal of …
2000
Neuroreport
1999
32 인용
Microscopy research and …
1998
26 인용
Journal of neurobiology
1996
45 인용
Molecular and chemical …
1996
17 인용
Journal of neuroscience …
1996
16 인용
Behavioural brain research
1995
146 인용
Developmental biology
1989
100 인용
Journal of steroid …
1984
22 인용
Brain research
1975
122 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 150-250 mg/day
- cognitivesupport:
- 250-500 mg sublingually
상한량: Not established; well-tolerated up to 1,000 mg/day
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Mixed | -- |
| None | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Neutral | -- |
| 5 mg/kg | 4 weeks | Positive | -- |
| 1 g | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
권장 복용 시간: Morning; synergizes with DHA and choline sources
Safety & Side Effects
보고된 부작용
- ⚠ Mild gastrointestinal discomfort
- ⚠ Headache (rare)
- ⚠ Nervousness at high doses
알려진 상호작용
- ● No significant drug interactions established
일일 최대 섭취 허용량: Not established; well-tolerated up to 1,000 mg/day
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Uridine Monophosphate help with Neurotransmitter Imbalance?
Based on 4 studies with 300 participants, there is limited but promising evidence that Uridine Monophosphate may support Neurotransmitter Imbalance management. Our evidence grade is C (Some Evidence).
How much Uridine Monophosphate should I take for Neurotransmitter Imbalance?
Studies have used various dosages. A commonly studied range is 150-250 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Uridine Monophosphate?
Reported side effects may include Mild gastrointestinal discomfort, Headache (rare), Nervousness at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Uridine Monophosphate and Neurotransmitter Imbalance?
We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 300 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: Neurotransmitter Imbalance
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