Figure 441

![Figure 441: Mediation analysis diagram illustrating the potential pathway through which docosahexaenoic acid (DHA) may influence ulcerative colitis (UC) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association.]()

> Source: Xiaojing Jia et al. "Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bo." *Metabolites*, 2023. PMID: [37887366](https://pubmed.ncbi.nlm.nih.gov/37887366/)

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  <img src="" alt="Mediation analysis diagram illustrating the potential pathway through which docosahexaenoic acid (DHA) may influence ulcerative colitis (UC) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association." />
  <figcaption>Figure 441. Mediation analysis diagram illustrating the potential pathway through which docosahexaenoic acid (DHA) may influence ulcerative colitis (UC) risk via circulating metabolites. Direct and indirect effects are quantified using two-step Mendelian randomization, highlighting metabolites that may partially mediate the observed association.<br>  Source: Xiaojing Jia et al. "Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bo." <em>Metabolites</em>, 2023. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/37887366/">37887366</a></figcaption>
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