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Introductory overview of the carotenoid compounds evaluated for neuroprotective effects in Alzheimer's disease. The review examines how these dietary pigments may counteract neurodegeneration through antioxidant and anti-inflammatory pathways.

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KEGG pathway map (hsa05010) illustrating the molecular cascade involved in Alzheimer's disease pathogenesis in humans. The diagram highlights potential intervention points where carotenoid compounds may modulate amyloid-beta accumulation, tau phosphorylation, and neuroinflammatory signaling.

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Figure 7

Evidence summary on the association between specific carotenoid compounds and Alzheimer's disease biomarkers. The data suggest that higher carotenoid status may be linked to reduced oxidative damage in neural tissues.

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Figure 22

Alpha- and beta-cryptoxanthin serve as provitamin A sources due to their unsubstituted beta-ring structure. The review discusses their potential role in Alzheimer's disease prevention through both antioxidant activity and vitamin A metabolite production in neural tissue.

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Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.

International journal of molecular sciences (2024)

PMID: 39201668

DOI: 10.3390/ijms25168982

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![Figure 2: Introductory overview of the carotenoid compounds evaluated for neuroprotective effects in Alzheimer's disease. The review examines how these dietary pigments may counteract neurodegeneration through antioxidant and anti-inflammatory pathways.](https://pdfs.citedhealth.com/figures/39201668/170.png)

> Source: Jolanta Flieger et al. "Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.." *International journal of molecular sciences*, 2024. PMID: [39201668](https://pubmed.ncbi.nlm.nih.gov/39201668/)

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  <img src="https://pdfs.citedhealth.com/figures/39201668/170.png" alt="Introductory overview of the carotenoid compounds evaluated for neuroprotective effects in Alzheimer's disease. The review examines how these dietary pigments may counteract neurodegeneration through antioxidant and anti-inflammatory pathways." />
  <figcaption>Figure 2. Introductory overview of the carotenoid compounds evaluated for neuroprotective effects in Alzheimer's disease. The review examines how these dietary pigments may counteract neurodegeneration through antioxidant and anti-inflammatory pathways.<br>  Source: Jolanta Flieger et al. "Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.." <em>International journal of molecular sciences</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/39201668/">39201668</a></figcaption>
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