What is the recommended dosage for Vitamin D?

General: 600-2,000 IU/day; Deficiency Correction: 4,000-5,000 IU/day

What are the side effects of Vitamin D?

Potential side effects include: Hypercalcemia at very high doses, Nausea and vomiting, Kidney stones (rare, high doses), Weakness and fatigue.

Vitamin D is a fat-soluble vitamin and neurosteroid hormone that plays a role in brain development and function. Vitamin D receptors are widely distributed throughout the brain. Research has associated low vitamin D status with increased risk of cognitive concerns, particularly in older adults.

What dosage of Vitamin D has been used in cognitive studies?

Cognitive studies have used 800 IU to 4,000 IU of vitamin D3 (cholecalciferol) daily. Some studies have targeted specific serum 25(OH)D levels, typically above 30 ng/mL. The tolerable upper intake is 4,000 IU per day for adults. Consult your healthcare provider and consider testing your levels.

What are the potential side effects of Vitamin D?

Vitamin D toxicity is rare but can occur with prolonged intake above 10,000 IU per day, causing hypercalcemia with symptoms including nausea, weakness, and kidney problems. Vitamin D may interact with certain heart and kidney medications. Consult your healthcare provider for appropriate dosing.

Vitamin D
Vitamin D

vitamin

다른 이름: Vitamin D3, Cholecalciferol, Calciferol, Ergocalciferol (D2)

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About

Vitamin D is a neurosteroid hormone with receptors throughout the brain, particularly in the hippocampus and cerebral cortex. Deficiency, which affects 40% of geriatric memory clinic patients, is identified as a critical risk factor for cognitive decline. Supplementation supports calcium signaling in neurons, neurotrophic factor expression, and protection against oxidative stress and inflammation.

How It Works

Neurosteroid hormone with receptors in the hippocampus and cerebral cortex; supports calcium signaling in neurons, neurotrophic factor expression, neurotransmitter synthesis, and neuronal protection against oxidative stress and inflammation.

Evidence For Conditions

건강 상태	등급	연구	참여자
Nutritional Deficiency Cognitive Impairment	B	20	4500	보기 →
Depression-Related Cognitive Dysfunction	C	12	2000	보기 →

Side Effects

Hypercalcemia at very high doses
Nausea and vomiting
Kidney stones (rare, high doses)
Weakness and fatigue

Drug & Supplement Interactions

Corticosteroids (reduce calcium absorption)
Statins (both affect cholesterol pathways)
Thiazide diuretics (additive calcium retention)
Weight loss drugs (may reduce vitamin D absorption)

복용 중인 모든 건강기능식품에 대해 반드시 의료 전문가에게 알리십시오.

Related Ingredients

Vitamin B6 Vitamin E Niacin Vitamin B12 Folate

핵심 정보

용량: General: 600-2,000 IU/day; Deficiency_Correction: 4,000-5,000 IU/day
제형: softgel capsule tablet drops gummy
천연 원료: Sunlight, Fatty fish, Fortified milk, Egg yolks, Mushrooms
상한 섭취량: 4,000 IU/day (IOM); 10,000 IU/day (Endocrine Society upper safety)
권장 복용 시간: With meals containing fat; morning preferred

근거 요약

Nutritional Deficiency Cognitive Impairment B

Depression-Related Cognitive Dysfunction C

FDA 면책 조항: 이 내용은 미국 식품의약국(FDA)의 평가를 받지 않았습니다. 이 웹사이트의 제품 및 정보는 질병의 진단, 치료, 완치 또는 예방을 목적으로 하지 않습니다. 제시된 근거 등급은 발표된 동료 심사 연구에 대한 우리의 분석에 기반하며, 의학적 조언을 구성하지 않습니다. 건강기능식품 복용을 시작하기 전에 반드시 의료 전문가와 상담하십시오.