Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation.

Airi Watanabe, Nobumasa Kato, Tadafumi Kato

Other Neuroscience research 2002 180 인용

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Study Design

연구 유형: Controlled Clinical Trial
표본 크기: 24
대상 집단: Healthy adults

중재: Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation. Creatine 8g/day for 5 days
대조군: Placebo
일차 결과: Mental fatigue and cerebral hemoglobin oxygenation
효과 방향: Positive
비뚤림 위험: Moderate

Abstract

While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. Creatine is abundant in muscles and the brain and after phosphorylation used as an energy source for adenosine triphosphate synthesis. Using double-blind placebo-controlled paradigm, we demonstrated that dietary supplement of creatine (8 g/day for 5 days) reduces mental fatigue when subjects repeatedly perform a simple mathematical calculation. After taking the creatine supplement, task-evoked increase of cerebral oxygenated hemoglobin in the brains of subjects measured by near infrared spectroscopy was significantly reduced, which is compatible with increased oxygen utilization in the brain.

요약

Using double-blind placebo-controlled paradigm, it is demonstrated that dietary supplement of creatine reduces mental fatigue when subjects repeatedly perform a simple mathematical calculation.

Used In Evidence Reviews

B Creatine 관련 Mental Fatigue

Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation.

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Study Design

Abstract

요약

Used In Evidence Reviews

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