What is the recommended dosage for Vitamin E?

General: 15 mg/day (RDA); Cognitive Support: 400-800 IU/day

What are the side effects of Vitamin E?

Potential side effects include: Increased bleeding risk at high doses, Nausea and diarrhea, Fatigue and weakness, Blurred vision.

Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage. The brain's high lipid content makes it particularly susceptible to oxidative stress. Research has explored vitamin E's potential role in supporting brain health, primarily through its alpha-tocopherol form.

What dosage of Vitamin E has been used in cognitive studies?

Cognitive studies have used doses ranging from 400 IU to 2,000 IU of alpha-tocopherol daily. Mixed tocopherol formulations including gamma-tocopherol are also available. The tolerable upper intake is 1,000 mg (approximately 1,500 IU) per day. Consult your healthcare provider before high-dose use.

What are the potential side effects of Vitamin E?

High-dose vitamin E supplementation (above 400 IU per day) has been associated with increased bleeding risk in some studies. It may interact with blood-thinning medications and vitamin K. Some meta-analyses have raised concerns about high-dose supplementation. Consult your healthcare provider.

Vitamin E
Vitamin E

vitamin

Также известен как: Alpha-Tocopherol, D-Alpha-Tocopherol, Mixed Tocopherols, Tocotrienols

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About

Vitamin E is a fat-soluble antioxidant that protects neuronal membranes from lipid peroxidation. High-dose vitamin E may slow functional decline in moderate Alzheimer's disease, though evidence for prevention is mixed.

How It Works

Fat-soluble antioxidant protecting polyunsaturated fatty acids in neuronal membranes; supports mitochondrial membrane integrity; alpha-tocopherol is the primary brain-active form.

Evidence For Conditions

Состояние	Оценка	Исследования	Участники
Age-Related Cognitive Decline	C	12	3000	Подробнее →

Side Effects

Increased bleeding risk at high doses
Nausea and diarrhea
Fatigue and weakness
Blurred vision

Drug & Supplement Interactions

Anticoagulants (increased bleeding risk)
Statins and niacin (may reduce HDL-raising effects)
Chemotherapy and radiation (may reduce efficacy)

Всегда сообщайте лечащему врачу обо всех принимаемых добавках.

Related Ingredients

Vitamin D Vitamin B6 Niacin Vitamin B12 Folate

Основные факты

Дозировка: General: 15 mg/day (RDA); Cognitive_Support: 400-800 IU/day
Формы выпуска: softgel capsule liquid
Природные источники: Nuts (almonds, hazelnuts), Seeds (sunflower), Vegetable oils, Spinach, Avocado
Верхний предел: 1,000 mg/day (1,500 IU natural / 1,100 IU synthetic)
Лучшее время приёма: With meals containing fat

Обзор доказательной базы

Age-Related Cognitive Decline C

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.