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[Atrial fibrillation after coronary artery bypass surgery: possibilities of prevention].

Biljana Obrenović-Kirćanski, Bojana Orbović, Mile Vraneš, Biljana Parapid, Nataša Kovačević-Kostić et al.
Review Srpski arhiv za celokupno lekarstvo 2012 3 trích dẫn
PubMed DOI
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Study Design

Loại nghiên cứu
Review
Đối tượng nghiên cứu
heart failure patients
Can thiệp
[Atrial fibrillation after coronary artery bypass surgery: possibilities of prevention]. None
Đối chứng
None
Kết quả chính
mortality
Xu hướng hiệu quả
Mixed
Nguy cơ sai lệch
Unclear

Abstract

Atrial fibrillation occurs as a frequent complication after cardiac interventions. It can be found in 5% of all surgical patients, and it is far more common in cardiac (10% - 65% of patients) than in non-cardiac procedures. In a number of patients it remains asymptomatic, but may be accompanied by very severe symptoms of hypotension, heart failure, syncope, systemic or pulmonary embolism, perioperative myocardial infarction, cerebrovascular insult and increased operative mortality. Patients whose postoperative course is complicated by atrial fibrillation require longer hospitalization. Possible predisposing factors of this arrhythmia are numerous and are associated with surgery, extensive coronary heart disease and revascularization, and preoperative diseases. According to the recommendations of the European Society of Cardiology orally applied beta-blocker, amiodarone and sotalol can be used for prophylaxis of atrial fibrillation. Following the recommendations, treatment of postoperative atrial fibrillation should include beta-blockers, amiodarone, and in patients with heart failure and left ventricular dysfunction, digoxin. Due to the increased risk of stroke, an anticoagulant protection is necessary. Many studies have been conducted with results supporting the prophylactic use of amiodarone and beta-blockers, while the treatment with new agents such as magnesium, statins, omega-3 fatty acids and inhibitors of the renin-angiotensin-aldosterone system is still being investigated.

Tóm lược

Treatment of postoperative atrial fibrillation should include beta-blockers, amiodarone, and in patients with heart failure and left ventricular dysfunction, digoxin, due to the increased risk of stroke, an anticoagulant protection is necessary.

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