Randomized Controlled Trials
Gold-standard experimental studies with random treatment allocation.
Use of Citicoline in Attention-Deficit/Hyperactivity Disorder: A Pilot Study.
Clinical neuropharmacology
2 citations
Changes in Resting-State Functional Connectivity and Cognitive-Affective Symptoms in Patients With Post-Concussion Syndrome Treated With N-Acetyl Cysteine.
The Journal of head trauma rehabilitation
Neuroprotective Effects of Alpha-Lipoic Acid Against Behavioral Toxicity, Oxidative and Inflammatory Damage Caused by Titanium Dioxide Nanoparticles.
Biological trace element research
2026
2 citations
Efficacy of Bacopa monnieri (Linn.) on Cognitive Function and Alterations in Blood Metabolites in Patients With Amnestic Mild Cognitive Impairment and Early Alzheimer Disease: Protocol for an Exploratory Double-Blind, Randomized, Placebo-Controlled Trial.
JMIR research protocols
2026
Effects of Bacopa monnieri herbal supplement on aging and neurocognitive functions, including neurophysiological assessments, in relation to constitution (Prakriti) in healthy adults: clinical trial protocol.
Frontiers in medicine
2026
The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.
Nutrients
2025
6 citations
Efficacy and associated neurotransmitters of digital cognitive behavior therapy for atopic dermatitis: A comparative effectiveness research.
Asian Pacific journal of allergy and immunology
2025
6 citations
Effectiveness of Autologous Platelet-Rich Plasma for Androgenetic Alopecia: A Double-Center, Non-Controlled, Randomized Clinical Study in Vietnam.
Clinical, cosmetic and investigational dermatology
2025
4 citations
Apolipoprotein E ε4-dependent associations between carotenoids and cognitive decline: Findings from the MIND (Mediterranean-DASH Intervention for Neurodegenerative delay) randomized controlled trial.
The American journal of clinical nutrition
2025
2 citations
Melatonin agonist tasimelteon (HETLIOZ®) improves sleep in patients with primary insomnia: A multicenter, randomized, double-blind, placebo-controlled trial.
PloS one
2025
1 citation
Centella asiatica improves sleep quality and quantity in aged mice.
bioRxiv : the preprint server for biology
2025
1 citation
Vitamin B12 supplementation attenuates endoplasmic reticulum stress and neuronal cell death in the cerebral cortex of high-fat high-sucrose-fed male mice.
Nutrition (Burbank, Los Angeles County, Calif.)
2025
Comparing the Efficacy of Combined Intralesional Triamcinolone Acetonide With Topical Calcipotriol Versus Intralesional Triamcinolone Acetonide Monotherapy in Scalp and Beard Alopecia Areata: Results From a Randomized Single-Blinded Clinical Trial.
Journal of cutaneous medicine and surgery
2025
Subchronic Residual Oil Fly Ash (ROFA) exposure induces oxidative stress in brain, lung, and cardiac tissues and promotes neuroinflammation, with partial attenuation by taurine.
Neurotoxicology
2025
CMX-2043 Treatment Limits Neural Injury Pathophysiology and Promotes Neurological and Cognitive Recovery in a Pediatric Porcine Traumatic Brain Injury Model.
Journal of neurotrauma
2025
[Verification of resveratrol ameliorating vascular endothelial damage in sepsis-associated encephalopathy through HIF-1α pathway based on network pharmacology and experiment].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
2025
Resveratrol restores indices of neurovascular coupling following acute sleep restriction in young men and women.
Journal of applied physiology (Bethesda, Md. : 1985)
2025
Pharmacodynamic and Clinical Effects of Ginkgo Biloba Extract EGb 761 and Its Phytochemical Components in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
2024
12 citations
Fish and Omega-3 Fatty Acids: Sex and Racial Differences in Cardiovascular Outcomes and Cognitive Function.
Arteriosclerosis, thrombosis, and vascular biology
2024
12 citations
Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease.
International journal of molecular sciences
2024
11 citations
Evidence and Perspectives for Choline Supplementation during Parenteral Nutrition-A Narrative Review.
Nutrients
2024
7 citations
Sex differences in lipid mediators derived from omega-3 fatty acids in older individuals with low-grade chronic inflammation.
Prostaglandins, leukotrienes, and essential fatty acids
2024
6 citations
The impact of six-week dihydrogen-pyrroloquinoline quinone supplementation on mitochondrial biomarkers, brain metabolism, and cognition in elderly individuals with mild cognitive impairment: a randomized controlled trial.
The journal of nutrition, health & aging
2024
6 citations
Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
Medicine
2024
3 citations
Clinical efficacy and mechanism of Ginkgo biloba extract in the treatment of elderly ischemic cerebrovascular disease.
Pakistan journal of pharmaceutical sciences
2024
2 citations
Associations between Cerebrovascular Function and the Expression of Genes Related to Endothelial Function in Hormonal Migraine.
International journal of molecular sciences
2024
1 citation
Intralesional vitamin D3 versus intralesional triamcinolone acetonoid in patchy alopecia areata: a comparative clinical and dermoscopic study.
Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology
2024
1 citation
Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials.
Journal of Parkinson's disease
2024
1 citation
A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress.
Scientific reports
2023
30 citations
Markers of Vitamin B12 Status in Relation to Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Cognitive Performance.
Annals of neurology
2023
15 citations
Vitamin B12 supplementation improves cognitive function in middle aged and elderly patients with cognitive impairment.
Nutricion hospitalaria
2023
13 citations
Effects of Long-Chain Polyunsaturated Fatty Acids in Combination with Lutein and Zeaxanthin on Episodic Memory in Healthy Older Adults.
Nutrients
2023
12 citations
A Randomized, Double-Blind, Placebo-Controlled, Parallel Study Investigating the Efficacy of a Whole Coffee Cherry Extract and Phosphatidylserine Formulation on Cognitive Performance of Healthy Adults with Self-Perceived Memory Problems.
Neurology and therapy
2023
9 citations
Targeting neuroendocrine abnormalities in Parkinson's disease with exercise.
Frontiers in neuroscience
2023
5 citations
Polo-like kinase inhibitor BI2536 induces eryptosis.
Wiener medizinische Wochenschrift (1946)
2023
4 citations
Alpha lipoic acid treatment in late middle age improves cognitive function: Proteomic analysis of the protective mechanisms in the hippocampus.
Neuroscience letters
2023
4 citations
Fractional carbon dioxide laser alone and as an assisted drug delivery for treatment of alopecia areata: a clinical, dermoscopic and immunohistochemical study.
Archives of dermatological research
2023
3 citations
Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B vitamins: an fMRI study.
Frontiers in nutrition
2023
3 citations
Efficacy of a mixture of Ginkgo biloba, sesame, and turmeric on cognitive function in healthy adults: Study protocol for a randomized, double-blind, placebo-controlled trial.
PloS one
2023
Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: A randomised clinical trial.
Clinical nutrition (Edinburgh, Scotland)
2022
87 citations
Omega-3 fatty acids and blood-based biomarkers in Alzheimer's disease and mild cognitive impairment: A randomized placebo-controlled trial.
Brain, behavior, and immunity
2022
64 citations
Zinc alters behavioral phenotypes, neurotransmitter signatures, and immune homeostasis in male zebrafish (Danio rerio).
The Science of the total environment
2022
11 citations
Alpha lipoic acid reverses scopolamine-induced spatial memory loss and pyramidal cell neurodegeneration in the prefrontal cortex of Wistar rats.
IBRO neuroscience reports
2022
11 citations
Resveratrol inhibits cerebral aneurysms in mice via downregulating the NF-κB pathway.
Acta biochimica Polonica
2022
10 citations
A Randomised, Double-Blind, Placebo-Controlled Crossover Trial of Resveratrol Supplementation for Prophylaxis of Hormonal Migraine.
Nutrients
2022
9 citations
α-Lipoic Acid Reduces Ceramide Synthesis and Neuroinflammation in the Hypothalamus of Insulin-Resistant Rats, While in the Cerebral Cortex Diminishes the β-Amyloid Accumulation.
Journal of inflammation research
2022
9 citations
Prolonging effects of Valeriana fauriei root extract on pentobarbital-induced sleep in caffeine-induced insomnia model mice and the pharmacokinetics of its active ingredients under conditions of glycerol fatty acid ester as emulsifiers.
Journal of ethnopharmacology
2022
8 citations
N -acetylcysteine is associated with reduction of postconcussive symptoms in elderly patients: A pilot study.
The journal of trauma and acute care surgery
2022
7 citations
Ginkgo biloba extract 761 reduces vascular permeability of the ovary and improves the symptom of ovarian hyperstimulation syndrome in a rat model.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
2022
6 citations
Ginkgo biloba extract 761 reduces vascular permeability of the ovary and improves the symptom of ovarian hyperstimulation syndrome in a rat model.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
2022
5 citations
Protection against Morphine-Induced Inhibitory Avoidance Memory Impairment in Rat by Curcumin: Possible Role of Nitric Oxide/ cAMP-Response Element Binding Protein Pathway.
Iranian journal of medical sciences
2022
5 citations
Comparative Study Between Intralesional Injection Of Platelet Rich Plasma And Intra Lesional Triamcinolone For The Treatment Of Alopecia Areata.
Journal of Ayub Medical College, Abbottabad : JAMC
2022
4 citations
Influence of a 12-Month Structured Exercise Program on the Micronutrient-Cognitive Fitness-Physical Association Profiles in Mild Cognitive Impairment.
Journal of Alzheimer's disease reports
2022
4 citations
Combination of platelet-rich plasma and platelet gel in treatment of resistance androgenic alopecia: A case series study.
Journal of cosmetic dermatology
2022
3 citations
Levetiracetam exposure during prenatal and postnatal period induces cognitive decline in rat offsprings, not completely prevented by Bacopa monnieri.
Journal of complementary & integrative medicine
2022
3 citations
Curcumin improves reversal learning in middle-aged rhesus monkeys.
Behavioral neuroscience
2022
2 citations
Melatonin ameliorates Parkinson's disease via regulating microglia polarization in a RORα-dependent pathway.
NPJ Parkinson's disease
2022
Enhancement of Swimming Endurance by Herbal Supplement M3P.
Chinese journal of integrative medicine
2022
Long-term effects of resveratrol on cognition, cerebrovascular function and cardio-metabolic markers in postmenopausal women: A 24-month randomised, double-blind, placebo-controlled, crossover study.
Clinical nutrition (Edinburgh, Scotland)
2021
54 citations
Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation.
The journal of pain
2021
41 citations
Higher circulating α-carotene was associated with better cognitive function: an evaluation among the MIND trial participants.
Journal of nutritional science
2021
26 citations
Retinal Venular Tortuosity Jointly with Retinal Amyloid Burden Correlates with Verbal Memory Loss: A Pilot Study.
Cells
2021
24 citations
Effectiveness and Safety Profile of Ginkgo biloba Standardized Extract (EGb761®) in Patients with Amnestic Mild Cognitive Impairment.
CNS & neurological disorders drug targets
2021
12 citations
Regular Supplementation With Resveratrol Improves Bone Mineral Density in Postmenopausal Women: A Randomized, Placebo-Controlled Trial.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
2020
120 citations
Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial.
EBioMedicine
2020
107 citations
Can Creatine Combat the Mental Fatigue-associated Decrease in Visuomotor Skills?
Medicine and science in sports and exercise
2020
63 citations
Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women.
Nutrients
2020
49 citations
Effects of Matcha Green Tea Powder on Cognitive Functions of Community-Dwelling Elderly Individuals.
Nutrients
2020
43 citations
Effects of L-theanine-caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT.
Scientific reports
2020
34 citations
Evaluation of Cognitive Performance following Fish-Oil and Curcumin Supplementation in Middle-Aged and Older Adults with Overweight or Obesity.
The Journal of nutrition
2020
33 citations
Comparative Evaluation of Therapeutic Efficacy of Intralesional Injection of Triamcinolone Acetonide versus Intralesional Autologous Platelet-rich Plasma Injection in Alopecia Areata.
Journal of cutaneous and aesthetic surgery
2020
21 citations
Effect of an oral preparation containing hyaluronic acid, chondroitin sulfate, hydrolyzed collagen type II and hydrolyzed keratin on synovial fluid features and clinical indices in knee osteoarthritis. A pilot study.
Reumatismo
2020
21 citations
Efficacy of Bacopa Monnieri (Brahmi) and Donepezil in Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Double-Blind Parallel Phase 2b Study.
Annals of Indian Academy of Neurology
2020
17 citations
Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
2020
5 citations
L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
Journal of psychiatric research
2019
46 citations
A Study to Compare the Efficacy of Platelet-rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia.
International journal of trichology
2019
41 citations
Combining a high DHA multi-nutrient supplement with aerobic exercise: Protocol for a randomised controlled study assessing mobility and cognitive function in older women.
Prostaglandins, leukotrienes, and essential fatty acids
2019
5 citations
Long-Term Efficacy and Safety of Pediatric Prolonged-Release Melatonin for Insomnia in Children with Autism Spectrum Disorder.
Journal of child and adolescent psychopharmacology
2018
133 citations
Cerebral Blood Flow Measurements in Adults: A Review on the Effects of Dietary Factors and Exercise.
Nutrients
2018
108 citations
Lutein and Zeaxanthin Influence Brain Function in Older Adults: A Randomized Controlled Trial.
Journal of the International Neuropsychological Society : JINS
2018
76 citations
Supplemental Retinal Carotenoids Enhance Memory in Healthy Individuals with Low Levels of Macular Pigment in A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Journal of Alzheimer's disease : JAD
2018
63 citations
Can Curcumin Counteract Cognitive Decline? Clinical Trial Evidence and Rationale for Combining ω-3 Fatty Acids with Curcumin.
Advances in nutrition (Bethesda, Md.)
2018
28 citations
Effects of Omega-3 Fatty Acids on Resting Cerebral Perfusion in Patients with Mild Cognitive Impairment: A Randomized Controlled Trial.
The journal of prevention of Alzheimer's disease
2018
24 citations
Immunotherapy of Mild Cognitive Impairment by ω-3 Supplementation: Why Are Amyloid-β Antibodies and ω-3 Not Working in Clinical Trials?
Journal of Alzheimer's disease : JAD
2018
12 citations
Protein Supplementation During or Following a Marathon Run Influences Post-Exercise Recovery.
Nutrients
2018
10 citations
Efficacy and Safety of Pediatric Prolonged-Release Melatonin for Insomnia in Children With Autism Spectrum Disorder.
Journal of the American Academy of Child and Adolescent Psychiatry
2017
245 citations
Effects of Resveratrol on Cognitive Performance, Mood and Cerebrovascular Function in Post-Menopausal Women; A 14-Week Randomised Placebo-Controlled Intervention Trial.
Nutrients
2017
149 citations
Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study.
Acta neuropsychiatrica
2017
84 citations
Resveratrol supplementation reduces pain experience by postmenopausal women.
Menopause (New York, N.Y.)
2017
47 citations
Phospholipid oxidation and carotenoid supplementation in Alzheimer's disease patients.
Free radical biology & medicine
2017
37 citations
Short-Term Impact of a Combined Nutraceutical on Cognitive Function, Perceived Stress and Depression in Young Elderly with Cognitive Impairment: A Pilot, Double-Blind, Randomized Clinical Trial.
The journal of prevention of Alzheimer's disease
2017
30 citations
Alopecia and platelet-derived therapies.
Stem cell investigation
2017
27 citations
Effects of sulforaphane and vitamin E on cognitive disorder and oxidative damage in lead-exposed mice hippocampus at lactation.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
2017
24 citations
Memory Complaints and Cognitive Decline: Data from the GUIDAGE Study1.
Journal of Alzheimer's disease : JAD
2017
17 citations
Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment.
Journal of Alzheimer's disease : JAD
2016
128 citations
Combined omega-3 fatty acids, aerobic exercise and cognitive stimulation prevents decline in gray matter volume of the frontal, parietal and cingulate cortex in patients with mild cognitive impairment.
NeuroImage
2016
118 citations
Low dose resveratrol improves cerebrovascular function in type 2 diabetes mellitus.
Nutrition, metabolism, and cardiovascular diseases : NMCD
2016
85 citations
Acute Resveratrol Consumption Improves Neurovascular Coupling Capacity in Adults with Type 2 Diabetes Mellitus.
Nutrients
2016
83 citations
DHA Supplementation Alone or in Combination with Other Nutrients Does not Modulate Cerebral Hemodynamics or Cognitive Function in Healthy Older Adults.
Nutrients
2016
53 citations
Effect of mitochondrial cofactors and antioxidants supplementation on cognition in the aged canine.
Neurobiology of aging
2016
19 citations