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Schematic diagram illustrating how microglia-derived myeloperoxidase transfers to neurons via exosomes, increasing neuronal HOCl production and facilitating HMGB1 release to amplify ischemic brain damage.
Figure 11
DiagramSource Paper
Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in …Cite This Figure
![Figure 11: Schematic diagram illustrating how microglia-derived myeloperoxidase transfers to neurons via exosomes, increasing neuronal HOCl production and facilitating HMGB1 release to amplify ischemic brain damage.]() > Source: Shuang Chen et al. "Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mob." *Journal of neuroinflammation*, 2024. PMID: [38515139](https://pubmed.ncbi.nlm.nih.gov/38515139/)
<figure> <img src="" alt="Schematic diagram illustrating how microglia-derived myeloperoxidase transfers to neurons via exosomes, increasing neuronal HOCl production and facilitating HMGB1 release to amplify ischemic brain damage." /> <figcaption>Figure 11. Schematic diagram illustrating how microglia-derived myeloperoxidase transfers to neurons via exosomes, increasing neuronal HOCl production and facilitating HMGB1 release to amplify ischemic brain damage.<br> Source: Shuang Chen et al. "Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mob." <em>Journal of neuroinflammation</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/38515139/">38515139</a></figcaption> </figure>