Description

Mechanistic diagram of how Ginkgo biloba extract (EGb 761) modulates mitochondrial biogenesis through PGC-1alpha signaling, AMPK activation, and SIRT1 deacetylase pathways.

Figure 13

Diagram

Source Paper

Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence.

Oxidative medicine and cellular longevity (2019)

PMID: 31214285

DOI: 10.1155/2019/9695412

Cite This Figure

![Figure 13: Mechanistic diagram of how Ginkgo biloba extract (EGb 761) modulates mitochondrial biogenesis through PGC-1alpha signaling, AMPK activation, and SIRT1 deacetylase pathways.]()

> Source: Imane Lejri et al. "Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Rel." *Oxidative medicine and cellular longevity*, 2019. PMID: [31214285](https://pubmed.ncbi.nlm.nih.gov/31214285/)

<figure>
  <img src="" alt="Mechanistic diagram of how Ginkgo biloba extract (EGb 761) modulates mitochondrial biogenesis through PGC-1alpha signaling, AMPK activation, and SIRT1 deacetylase pathways." />
  <figcaption>Figure 13. Mechanistic diagram of how Ginkgo biloba extract (EGb 761) modulates mitochondrial biogenesis through PGC-1alpha signaling, AMPK activation, and SIRT1 deacetylase pathways.<br>  Source: Imane Lejri et al. "Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Rel." <em>Oxidative medicine and cellular longevity</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/31214285/">31214285</a></figcaption>
</figure>

Related Evidence

Ginkgo biloba for Age-Related Cognitive Decline

Grade C · 40 studies