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Melatonin has multiorgan effects.

Lionel H Opie, Sandrine Lecour
Review European heart journal. Cardiovascular pharmacotherapy 2016 77 sitasi
PubMed DOI
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Study Design

Jenis Studi
Review
Populasi
General population (melatonin multiorgan effects)
Intervensi
Melatonin has multiorgan effects. None
Pembanding
None
Luaran Utama
None
Arah Efek
Mixed
Risiko Bias
Unclear

Abstract

Melatonin, widely used to counter transatlantic travel jet lag and insomnia, is synthesized in the suprachiasmatic nucleus of the anterior pituitary gland. Its release into the circulation is stimulated by the onset of darkness, followed by a progressive decrease in blood levels with the onset of dawn. Melatonin administration can maintain the quality of sleep and help to counteract age-induced cognitive decline. Melatonin can also limit the severity of a variety of cardiovascular and cerebrovascular diseases, diabetes, and cancer.

TL;DR

Melatonin administration can maintain the quality of sleep and help to counteract age-induced cognitive decline, and limit the severity of a variety of cardiovascular and cerebrovascular diseases, diabetes, and cancer.

Used In Evidence Reviews

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