What is the recommended dosage for Vitamin E?

General: 15 mg/day (RDA); Cognitive Support: 400-800 IU/day

What are the side effects of Vitamin E?

Potential side effects include: Increased bleeding risk at high doses, Nausea and diarrhea, Fatigue and weakness, Blurred vision.

Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage. The brain's high lipid content makes it particularly susceptible to oxidative stress. Research has explored vitamin E's potential role in supporting brain health, primarily through its alpha-tocopherol form.

What dosage of Vitamin E has been used in cognitive studies?

Cognitive studies have used doses ranging from 400 IU to 2,000 IU of alpha-tocopherol daily. Mixed tocopherol formulations including gamma-tocopherol are also available. The tolerable upper intake is 1,000 mg (approximately 1,500 IU) per day. Consult your healthcare provider before high-dose use.

What are the potential side effects of Vitamin E?

High-dose vitamin E supplementation (above 400 IU per day) has been associated with increased bleeding risk in some studies. It may interact with blood-thinning medications and vitamin K. Some meta-analyses have raised concerns about high-dose supplementation. Consult your healthcare provider.

Vitamin E
Vitamin E

vitamin

Também conhecido como: Alpha-Tocopherol, D-Alpha-Tocopherol, Mixed Tocopherols, Tocotrienols

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About

Vitamin E is a fat-soluble antioxidant that protects neuronal membranes from lipid peroxidation. High-dose vitamin E may slow functional decline in moderate Alzheimer's disease, though evidence for prevention is mixed.

How It Works

Fat-soluble antioxidant protecting polyunsaturated fatty acids in neuronal membranes; supports mitochondrial membrane integrity; alpha-tocopherol is the primary brain-active form.

Evidence For Conditions

Condição	Nota	Estudos	Participantes
Age-Related Cognitive Decline	C	12	3000	Ver →

Side Effects

Increased bleeding risk at high doses
Nausea and diarrhea
Fatigue and weakness
Blurred vision

Drug & Supplement Interactions

Anticoagulants (increased bleeding risk)
Statins and niacin (may reduce HDL-raising effects)
Chemotherapy and radiation (may reduce efficacy)

Informe sempre o seu profissional de saúde sobre todos os suplementos que você toma.Sempre informe seu profissional de saúde sobre todos os suplementos que você toma.

Related Ingredients

Vitamin D Vitamin B6 Niacin Vitamin B12 Folate

Dados Rápidos

Dosagem: General: 15 mg/day (RDA); Cognitive_Support: 400-800 IU/day
Formas: softgel capsule liquid
Fontes Naturais: Nuts (almonds, hazelnuts), Seeds (sunflower), Vegetable oils, Spinach, Avocado
Limite Superior: 1,000 mg/day (1,500 IU natural / 1,100 IU synthetic)
Melhor Horário: With meals containing fat

Resumo das Evidências

Age-Related Cognitive Decline C

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.