Baseado em Evidências Avaliações de Suplementos
Every brain claim cited.
We read the cognitive health studies so you don't have to.
Evidence-based supplement research you can trust. We analyze peer-reviewed clinical studies from PubMed and grade every supplement ingredient on a transparent A–D scale. No sponsored rankings, no manufacturer influence — just science.
Featured Ingredients
Lion's Mane Mushroom
mushroomContains bioactive hericenones and erinacines that stimulate nerve growth factor (NGF) synthesis; promotes neurogenesis and myelination; supports hippocampal function and …
Phosphatidylserine
nootropicEssential phospholipid component of neuronal cell membranes; supports cell-to-cell communication, neurotransmitter release (acetylcholine, dopamine), and cortisol regulation; maintains membrane fluidity …
Curcumin
antioxidantCrosses the blood-brain barrier in enhanced forms; binds to amyloid-beta plaques reducing aggregation; reduces tau phosphorylation; exhibits potent anti-neuroinflammatory effects; …
Magnesium L-Threonate
mineralThe only magnesium form demonstrated to effectively cross the blood-brain barrier; increases synaptic density in hippocampal and prefrontal regions; enhances …
Rhodiola rosea
herbAdaptogenic herb that modulates cortisol and stress-response pathways via the HPA axis; active compounds rosavin and salidroside enhance monoamine neurotransmitter …
Omega-3 Fatty Acids (DHA/EPA)
fatty_acidSupports neuronal membrane integrity and fluidity; DHA constitutes approximately 40% of polyunsaturated fatty acids in the brain, supporting synaptic function, …
Top Conditions
Anxiety-Related Cognitive Impairment
Anxiety disorders affect 19% of US adults annually
Age-Related Cognitive Decline
Affects virtually all adults to some degree after age 50
Brain Fog
Reported by 20-30% of the general population
Attention & Focus Difficulties
Among the most reported cognitive complaints across all age groups
Mental Fatigue
Highly prevalent in modern knowledge-work environments
Sleep-Related Cognitive Impairment
35% of adults sleep less than 7 hours; 50-70 million have sleep disorders
Recent Evidence Updates
10 estudos
8 estudos
12 estudos
6 estudos
10 estudos
Popular Comparisons
Latest Research
J Sleep Res · 2017
European guideline for the diagnosis and treatment of insomnia.
Pflugers Arch · 2010
Glutamate receptors, neurotoxicity and neurodegeneration.
Pharmacol Res · 1999
Health benefits of docosahexaenoic acid (DHA).
Cell Mol Life Sci · 2005
Surface exposure of phosphatidylserine in pathological cells.
J Neurosci · 2000
Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen.
Circulation · 2010
OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction.
Guides & Resources
Exercise and Brain Health: How Physical Activity Supports Cognitive Function
Physical exercise is one of the most robustly supported interventions for brain health, with evidence spanning epidemiological studies, randomized controlled trials, and mechanistic neuroscience research. …
lifestyleSleep and Cognitive Performance: Why Rest Is Your Brain's Best Nootropic
Sleep is arguably the single most important factor in cognitive performance, yet it remains the most frequently sacrificed in pursuit of productivity. During sleep, the …
safetyCaffeine and L-Theanine: Synergy, Dosing, and Important Cautions
The combination of caffeine and L-theanine is often cited as the most well-studied nootropic stack, and for good reason. Multiple randomized controlled trials have demonstrated …
Evidence Grading System
Every supplement claim on this site is graded on an A–D scale based on peer-reviewed clinical research from PubMed. Our algorithm evaluates study design (RCTs rank highest), consistency of results, sample sizes, and the overall body of evidence. No manufacturer sponsorship influences our grades.
Multiple randomized controlled trials (RCTs) or meta-analyses with consistent positive results and large sample sizes.
At least one RCT with mostly consistent results across studies. Evidence suggests benefit but more research may be needed.
Small studies or observational data with some positive signals. Promising but insufficient for strong recommendations.
In vitro studies, case reports, or pilot studies only. Early-stage research that requires clinical validation.
How It Works
Sem anúncios. Sem rankings patrocinados. Apenas ciência.
Hub de pesquisa
Pesquisamos no PubMed cada estudo clínico sobre ingredientes de suplementos.
Extração
Extraímos as principais conclusões — dimensões das amostras, tipos de estudo e resultados.
Graus A a F
Classificamos a evidência como uma caderneta escolar — de A (forte) a F (negativo).
Resposta clara
Obtenha uma resposta clara em segundos — este suplemento realmente funciona?
Cited Health Network
Explore evidence-based research across multiple health domains.
Evidence-based hair supplement reviews. Every claim backed by peer-reviewed rese
SleepCitedEvidence-based sleep supplement reviews. Every claim backed by peer-reviewed res
GutCitedEvidence-based gut health supplement reviews. Every claim about probiotics, preb
ImmuneCitedEvidence-based immune supplement reviews. Every claim about vitamin C, zinc, eld
WeightCitedEvidence-based weight management supplement reviews. Every claim about green tea
HeartCitedEvidence-based cardiovascular supplement reviews. Every claim about omega-3, CoQ
SkinCitedEvidence-based skin health supplement reviews. Every claim about collagen, vitam
Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.