循证 补充剂评测
Every brain claim cited.
We read the cognitive health studies so you don't have to.
Evidence-based supplement research you can trust. We analyze peer-reviewed clinical studies from PubMed and grade every supplement ingredient on a transparent A–D scale. No sponsored rankings, no manufacturer influence — just science.
Featured Ingredients
Lion's Mane Mushroom
mushroomContains bioactive hericenones and erinacines that stimulate nerve growth factor (NGF) synthesis; promotes neurogenesis and myelination; supports hippocampal function and …
Phosphatidylserine
nootropicEssential phospholipid component of neuronal cell membranes; supports cell-to-cell communication, neurotransmitter release (acetylcholine, dopamine), and cortisol regulation; maintains membrane fluidity …
Curcumin
antioxidantCrosses the blood-brain barrier in enhanced forms; binds to amyloid-beta plaques reducing aggregation; reduces tau phosphorylation; exhibits potent anti-neuroinflammatory effects; …
Magnesium L-Threonate
mineralThe only magnesium form demonstrated to effectively cross the blood-brain barrier; increases synaptic density in hippocampal and prefrontal regions; enhances …
Rhodiola rosea
herbAdaptogenic herb that modulates cortisol and stress-response pathways via the HPA axis; active compounds rosavin and salidroside enhance monoamine neurotransmitter …
Omega-3 Fatty Acids (DHA/EPA)
fatty_acidSupports neuronal membrane integrity and fluidity; DHA constitutes approximately 40% of polyunsaturated fatty acids in the brain, supporting synaptic function, …
Top Conditions
Anxiety-Related Cognitive Impairment
Anxiety disorders affect 19% of US adults annually
Age-Related Cognitive Decline
Affects virtually all adults to some degree after age 50
Brain Fog
Reported by 20-30% of the general population
Attention & Focus Difficulties
Among the most reported cognitive complaints across all age groups
Mental Fatigue
Highly prevalent in modern knowledge-work environments
Sleep-Related Cognitive Impairment
35% of adults sleep less than 7 hours; 50-70 million have sleep disorders
Recent Evidence Updates
Popular Comparisons
Latest Research
J Sleep Res · 2017
European guideline for the diagnosis and treatment of insomnia.
Pflugers Arch · 2010
Glutamate receptors, neurotoxicity and neurodegeneration.
Pharmacol Res · 1999
Health benefits of docosahexaenoic acid (DHA).
Cell Mol Life Sci · 2005
Surface exposure of phosphatidylserine in pathological cells.
J Neurosci · 2000
Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen.
Circulation · 2010
OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction.
Guides & Resources
Exercise and Brain Health: How Physical Activity Supports Cognitive Function
Physical exercise is one of the most robustly supported interventions for brain health, with evidence spanning epidemiological studies, randomized controlled trials, and mechanistic neuroscience research. …
lifestyleSleep and Cognitive Performance: Why Rest Is Your Brain's Best Nootropic
Sleep is arguably the single most important factor in cognitive performance, yet it remains the most frequently sacrificed in pursuit of productivity. During sleep, the …
safetyCaffeine and L-Theanine: Synergy, Dosing, and Important Cautions
The combination of caffeine and L-theanine is often cited as the most well-studied nootropic stack, and for good reason. Multiple randomized controlled trials have demonstrated …
Evidence Grading System
Every supplement claim on this site is graded on an A–D scale based on peer-reviewed clinical research from PubMed. Our algorithm evaluates study design (RCTs rank highest), consistency of results, sample sizes, and the overall body of evidence. No manufacturer sponsorship influences our grades.
Multiple randomized controlled trials (RCTs) or meta-analyses with consistent positive results and large sample sizes.
At least one RCT with mostly consistent results across studies. Evidence suggests benefit but more research may be needed.
Small studies or observational data with some positive signals. Promising but insufficient for strong recommendations.
In vitro studies, case reports, or pilot studies only. Early-stage research that requires clinical validation.
How It Works
无广告。无赞助排名。只有科学。
研究中心
我们在 PubMed 上检索每一项关于补充剂成分的临床研究。
提取
我们提取关键发现——样本量、研究类型和结果。
A 至 F 级
我们像成绩单一样对证据进行分级——从 A（有力）到 F（阴性）。
明确答案
几秒内获得明确答案——这种补充剂是否真的有效？
Cited Health Network
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FDA 免责声明: 这些声明未经美国食品药品监督管理局（FDA）评估。本网站上的产品和信息无意用于诊断、治疗、治愈或预防任何疾病。所展示的证据等级基于我们对已发表的同行评审研究的分析，不构成医疗建议。在开始任何补充剂方案之前，请务必咨询您的医疗保健提供者。