[Advances in the researches of lutein and alzheimer's disease].

Xianrong Xu, Xiaoming Lin

Review Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 2015 4 citações

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Study Design

Tipo de Estudo: Review
População: Alzheimer's disease patients

Intervenção: [Advances in the researches of lutein and alzheimer's disease]. None
Comparador: None
Desfecho Primário: None
Direção do Efeito: Positive
Risco de Viés: Unclear

Abstract

Lutein, a kind of oxycarotenoid, can pass the blood brain barrier and preferentially accumulate in the human brain, which is the most abundant carotenoid in human brain. Evidence from multiple studies suggested that lutein was closely related to age-related cognitive decline and risk of Alzheimer's disease (AD) in human. Dietary, plasma and brain concentrations of lutein were negatively associated with age-related cognitive decline. Lutein concentrations in plasma and brain were significantly lower in AD patients than those of health control. In human brain, lutein was the sole carotenoid which consistently associated with a range of cognitive function measures. In elderly women, lutein supplement can improve the cognitive function. In this article, we systematically reviewed the literature on the role of lutein in age-related cognitive decline and alzheimer's disease and its possible mechanisms. It may prove some benefit information for the advanced research and prevention of AD.

Resumo Rápido

A systematically reviewed the literature on the role of lutein in age-related cognitive decline and alzheimer's disease and its possible mechanisms and may prove some benefit information for the advanced research and prevention of AD.

Used In Evidence Reviews

C Lutein & Zeaxanthin para Age-Related Cognitive Decline

[Advances in the researches of lutein and alzheimer's disease].

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Study Design

Abstract

Resumo Rápido

Used In Evidence Reviews

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