Melatonin has multiorgan effects.

Lionel H Opie, Sandrine Lecour

Review European heart journal. Cardiovascular pharmacotherapy 2016 77 citações

<\/script>\n

`; }, get iframeSnippet() { const domain = 'braincited.com'; const params = 'pmid\u003D27533945'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

Study Design

Tipo de Estudo: Review
População: General population (melatonin multiorgan effects)

Intervenção: Melatonin has multiorgan effects. None
Comparador: None
Desfecho Primário: None
Direção do Efeito: Mixed
Risco de Viés: Unclear

Abstract

Melatonin, widely used to counter transatlantic travel jet lag and insomnia, is synthesized in the suprachiasmatic nucleus of the anterior pituitary gland. Its release into the circulation is stimulated by the onset of darkness, followed by a progressive decrease in blood levels with the onset of dawn. Melatonin administration can maintain the quality of sleep and help to counteract age-induced cognitive decline. Melatonin can also limit the severity of a variety of cardiovascular and cerebrovascular diseases, diabetes, and cancer.

Resumo Rápido

Melatonin administration can maintain the quality of sleep and help to counteract age-induced cognitive decline, and limit the severity of a variety of cardiovascular and cerebrovascular diseases, diabetes, and cancer.

Used In Evidence Reviews

C Melatonin para Sleep-Related Cognitive Impairment

Melatonin has multiorgan effects.

Embed This Widget

Study Design

Abstract

Resumo Rápido

Used In Evidence Reviews

Similar Papers

European guideline for the diagnosis and treatment of insomnia.

Melatonin and the pineal gland: influence on mammalian seasonal and circadian physiology.

A review of sleep disorders and melatonin.

Review of Safety and Efficacy of Sleep Medicines in Older Adults.

Dietary Sources and Bioactivities of Melatonin.

Valerian extract and valerenic acid are partial agonists of the 5-HT5a receptor in vitro.