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Longitudinal metabolite analysis in the APPswe x PS1de9 transgenic mouse model of Alzheimer's disease, comparing metabolite levels across different age groups. These profiles indicate progressive neuroinflammatory changes in affected brain regions.

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![Figure 51: Longitudinal metabolite analysis in the APPswe x PS1de9 transgenic mouse model of Alzheimer's disease, comparing metabolite levels across different age groups. These profiles indicate progressive neuroinflammatory changes in affected brain regions.]()

> Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." *Journal of neurochemistry*, 2018. PMID: [29124761](https://pubmed.ncbi.nlm.nih.gov/29124761/)
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  <img src="" alt="Longitudinal metabolite analysis in the APPswe x PS1de9 transgenic mouse model of Alzheimer's disease, comparing metabolite levels across different age groups. These profiles indicate progressive neuroinflammatory changes in affected brain regions." />
  <figcaption>Figure 51. Longitudinal metabolite analysis in the APPswe x PS1de9 transgenic mouse model of Alzheimer's disease, comparing metabolite levels across different age groups. These profiles indicate progressive neuroinflammatory changes in affected brain regions.<br>  Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." <em>Journal of neurochemistry</em>, 2018. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29124761/">29124761</a></figcaption>
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