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NF-kB signaling pathway activation in iron-overloaded microglia is assessed, showing that ALA attenuates nuclear translocation and downstream inflammatory gene expression.
Figure 7
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Neuroprotective Role of α-Lipoic Acid in Iron-Overload-Mediated Toxicity and Inflammation in In Vitro and In Vivo Models.Cite This Figure
![Figure 7: NF-kB signaling pathway activation in iron-overloaded microglia is assessed, showing that ALA attenuates nuclear translocation and downstream inflammatory gene expression.]() > Source: Giuseppe Carota et al. "Neuroprotective Role of α-Lipoic Acid in Iron-Overload-Mediated Toxicity and Inf." *Antioxidants (Basel, Switzerland)*, 2022. PMID: [36009316](https://pubmed.ncbi.nlm.nih.gov/36009316/)
<figure> <img src="" alt="NF-kB signaling pathway activation in iron-overloaded microglia is assessed, showing that ALA attenuates nuclear translocation and downstream inflammatory gene expression." /> <figcaption>Figure 7. NF-kB signaling pathway activation in iron-overloaded microglia is assessed, showing that ALA attenuates nuclear translocation and downstream inflammatory gene expression.<br> Source: Giuseppe Carota et al. "Neuroprotective Role of α-Lipoic Acid in Iron-Overload-Mediated Toxicity and Inf." <em>Antioxidants (Basel, Switzerland)</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36009316/">36009316</a></figcaption> </figure>