What is the recommended dosage for Alpha-GPC?

General: 300-600 mg/day; Cognitive Support: 600-1,200 mg/day

What are the side effects of Alpha-GPC?

Potential side effects include: Headache, Insomnia, Dizziness, Gastrointestinal discomfort, Fishy body odor at high doses (TMAO conversion).

Alpha-GPC (alpha-glycerophosphocholine) is a choline-containing compound that serves as a precursor to the neurotransmitter acetylcholine. It is one of the most bioavailable forms of choline and has been studied for its potential role in supporting memory and cognitive function.

What dosage of Alpha-GPC has been used in studies?

Clinical studies have used doses ranging from 300 mg to 1,200 mg per day. A common dosage in cognitive research is 400 mg taken three times daily (1,200 mg total). Consult your healthcare provider for appropriate dosing.

What are the potential side effects of Alpha-GPC?

Alpha-GPC is generally well tolerated. Some people may experience headache, heartburn, insomnia, or dizziness. It may interact with anticholinergic medications. Consult your healthcare provider before taking Alpha-GPC, especially if you are on prescription medications.

Alpha-GPC
Alpha-GPC

choline_source

Aussi connu sous le nom de: Alpha-Glycerylphosphorylcholine, L-Alpha Glycerylphosphorylcholine, Choline Alfoscerate

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About

Alpha-GPC is a highly bioavailable choline source that crosses the blood-brain barrier to serve as a precursor for acetylcholine, the primary neurotransmitter for learning and memory. Clinical studies in elderly patients show improvements in cognitive function scores, and it is used as a prescription drug in several European countries.

How It Works

Provides highly bioavailable choline that crosses the blood-brain barrier; serves as a precursor to acetylcholine, the primary neurotransmitter for learning and memory; promotes neural tissue health and enhances neuronal communication.

Evidence For Conditions

Pathologie	Note	Études	Participants
Neurotransmitter Imbalance	B	10	800	Voir →
Age-Related Cognitive Decline	C	8	600	Voir →

Side Effects

Headache
Insomnia
Dizziness
Gastrointestinal discomfort
Fishy body odor at high doses (TMAO conversion)

Drug & Supplement Interactions

Anticholinergic medications (opposes Alpha-GPC effects)
Cholinesterase inhibitors (additive cholinergic effects)
Scopolamine (opposes cholinergic effects)

Informez toujours votre professionnel de santé de tous les compléments alimentaires que vous prenez.Informez toujours votre professionnel de santé de tous les compléments que vous prenez.

Related Ingredients

Choline Bitartrate

En bref

Posologie: General: 300-600 mg/day; Cognitive_Support: 600-1,200 mg/day
Formes: capsule powder liquid
Sources naturelles: Trace amounts in dairy, organ meats, and soy, Concentrated form extracted from soy lecithin
Limite supérieure: Not established; well-tolerated up to 1,200 mg/day
Meilleur moment: Morning or split dose; with or without food

Synthèse des preuves

Neurotransmitter Imbalance B

Age-Related Cognitive Decline C

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.