Figure 1

![Figure 1: Alzheimer's disease involves a complex pathological cascade initially triggered by amyloid-beta accumulation or aberrant APP processing. This figure argues for pleiotropic interventions that simultaneously target multiple pathological mechanisms rather than single molecular targets.](https://pdfs.citedhealth.com/figures/20437209/104.png)

> Source: Sally A Frautschy et al. "Why pleiotropic interventions are needed for Alzheimer's disease.." *Molecular neurobiology*, 2010. PMID: [20437209](https://pubmed.ncbi.nlm.nih.gov/20437209/)

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  <img src="https://pdfs.citedhealth.com/figures/20437209/104.png" alt="Alzheimer's disease involves a complex pathological cascade initially triggered by amyloid-beta accumulation or aberrant APP processing. This figure argues for pleiotropic interventions that simultaneously target multiple pathological mechanisms rather than single molecular targets." />
  <figcaption>Figure 1. Alzheimer's disease involves a complex pathological cascade initially triggered by amyloid-beta accumulation or aberrant APP processing. This figure argues for pleiotropic interventions that simultaneously target multiple pathological mechanisms rather than single molecular targets.<br>  Source: Sally A Frautschy et al. "Why pleiotropic interventions are needed for Alzheimer's disease.." <em>Molecular neurobiology</em>, 2010. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/20437209/">20437209</a></figcaption>
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