**Figure 3.** Figure 4. (A) Comparative analyses of main lipid classes and fatty acid contents and relevant indices between control and PD frontal cortex gray matter. Results are expressed as percent of change versus NSL group. Eight cases were analyzed in each group. *P < 0.1 and P < 0.05, respectively. (B) Analyses of the lipid raft-to-cortex ratios for representative lipid classes and fatty acid contents as well as for representative indices in the NSL and PD groups. Cortical and lipid raft were processed individually for each case. *P < 0.05,

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Comparative analyses of main lipid classes and fatty acid content between control and PD frontal cortex gray matter reveal disease-associated shifts in polyunsaturated fatty acid profiles and raft lipid indices.

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$Western blot analyses of protein markers across density gradient fractions from control, Parkinson's disease, and incidental PD brain cortices reveal altered lipid raft protein distribution.$

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Western blot analyses of protein markers across density gradient fractions from control, Parkinson's disease, and incidental PD brain cortices reveal altered lipid raft protein distribution.

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$Lipid composition analyses comparing raft and non-raft fractions between control and Parkinson's disease frontal cortex samples show significant alterations in cholesterol and sphingolipid content.$

Figure 2

Lipid composition analyses comparing raft and non-raft fractions between control and Parkinson's disease frontal cortex samples show significant alterations in cholesterol and sphingolipid content.

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Severe alterations in lipid composition of frontal cortex lipid rafts from Parkinson's disease and incidental Parkinson's disease.

Molecular medicine (Cambridge, Mass.) (2011)

PMID: 21717034

DOI: 10.2119/molmed.2011.00119

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![Figure 3: Comparative analyses of main lipid classes and fatty acid content between control and PD frontal cortex gray matter reveal disease-associated shifts in polyunsaturated fatty acid profiles and raft lipid indices.](https://pdfs.citedhealth.com/figures/21717034/185.png)

> Source: Noemí Fabelo et al. "Severe alterations in lipid composition of frontal cortex lipid rafts from Parki." *Molecular medicine (Cambridge, Mass.)*, 2011. PMID: [21717034](https://pubmed.ncbi.nlm.nih.gov/21717034/)

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  <img src="https://pdfs.citedhealth.com/figures/21717034/185.png" alt="Comparative analyses of main lipid classes and fatty acid content between control and PD frontal cortex gray matter reveal disease-associated shifts in polyunsaturated fatty acid profiles and raft lipid indices." />
  <figcaption>Figure 3. Comparative analyses of main lipid classes and fatty acid content between control and PD frontal cortex gray matter reveal disease-associated shifts in polyunsaturated fatty acid profiles and raft lipid indices.<br>  Source: Noemí Fabelo et al. "Severe alterations in lipid composition of frontal cortex lipid rafts from Parki." <em>Molecular medicine (Cambridge, Mass.)</em>, 2011. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/21717034/">21717034</a></figcaption>
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