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Longitudinal metabolite concentration data from the APPswe x PS1de9 Alzheimer's mouse model, revealing time-dependent changes in brain metabolic profiles. These measurements support the association between neuroinflammation and metabolic dysregulation.

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![Figure 82: Longitudinal metabolite concentration data from the APPswe x PS1de9 Alzheimer's mouse model, revealing time-dependent changes in brain metabolic profiles. These measurements support the association between neuroinflammation and metabolic dysregulation.]()

> Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." *Journal of neurochemistry*, 2018. PMID: [29124761](https://pubmed.ncbi.nlm.nih.gov/29124761/)
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  <img src="" alt="Longitudinal metabolite concentration data from the APPswe x PS1de9 Alzheimer's mouse model, revealing time-dependent changes in brain metabolic profiles. These measurements support the association between neuroinflammation and metabolic dysregulation." />
  <figcaption>Figure 82. Longitudinal metabolite concentration data from the APPswe x PS1de9 Alzheimer's mouse model, revealing time-dependent changes in brain metabolic profiles. These measurements support the association between neuroinflammation and metabolic dysregulation.<br>  Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." <em>Journal of neurochemistry</em>, 2018. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29124761/">29124761</a></figcaption>
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