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Brain metabolite measurements from APPswe x PS1de9 transgenic mice at multiple time points, providing evidence for progressive metabolic disruption linked to neuroinflammation. The data suggest region-specific vulnerability in this Alzheimer's disease model.
Figure 72
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Longitudinal investigation of neuroinflammation and metabolite profiles in the APPswe ×PS1Δe9 transgenic mouse model of Alzheimer's disease.Cite This Figure
![Figure 72: Brain metabolite measurements from APPswe x PS1de9 transgenic mice at multiple time points, providing evidence for progressive metabolic disruption linked to neuroinflammation. The data suggest region-specific vulnerability in this Alzheimer's disease model.]() > Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." *Journal of neurochemistry*, 2018. PMID: [29124761](https://pubmed.ncbi.nlm.nih.gov/29124761/)
<figure> <img src="" alt="Brain metabolite measurements from APPswe x PS1de9 transgenic mice at multiple time points, providing evidence for progressive metabolic disruption linked to neuroinflammation. The data suggest region-specific vulnerability in this Alzheimer's disease model." /> <figcaption>Figure 72. Brain metabolite measurements from APPswe x PS1de9 transgenic mice at multiple time points, providing evidence for progressive metabolic disruption linked to neuroinflammation. The data suggest region-specific vulnerability in this Alzheimer's disease model.<br> Source: Aisling Chaney et al. "Longitudinal investigation of neuroinflammation and metabolite profiles in the A." <em>Journal of neurochemistry</em>, 2018. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/29124761/">29124761</a></figcaption> </figure>