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SIRT1 expression levels are measured in Alzheimer's disease model cells treated with BDMC. Upregulation of SIRT1 protein and mRNA levels suggests a mechanism for BDMC's neuroprotective effects.
Figure 3
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Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1.Cite This Figure
![Figure 3: SIRT1 expression levels are measured in Alzheimer's disease model cells treated with BDMC. Upregulation of SIRT1 protein and mRNA levels suggests a mechanism for BDMC's neuroprotective effects.]() > Source: Yan Xu et al. "Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disea." *Brain and behavior*, 2020. PMID: [32441492](https://pubmed.ncbi.nlm.nih.gov/32441492/)
<figure> <img src="" alt="SIRT1 expression levels are measured in Alzheimer's disease model cells treated with BDMC. Upregulation of SIRT1 protein and mRNA levels suggests a mechanism for BDMC's neuroprotective effects." /> <figcaption>Figure 3. SIRT1 expression levels are measured in Alzheimer's disease model cells treated with BDMC. Upregulation of SIRT1 protein and mRNA levels suggests a mechanism for BDMC's neuroprotective effects.<br> Source: Yan Xu et al. "Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disea." <em>Brain and behavior</em>, 2020. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32441492/">32441492</a></figcaption> </figure>