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Dose-response data from the valerian extract murine study illustrate the relationship between extract concentration and sleep-related outcomes. The graded response pattern supports a pharmacological mechanism involving GABA and serotonin receptor pathways.

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![Figure 26: Dose-response data from the valerian extract murine study illustrate the relationship between extract concentration and sleep-related outcomes. The graded response pattern supports a pharmacological mechanism involving GABA and serotonin receptor pathways.]()

> Source: Kazim Sahin et al. "Impact of a Novel Valerian Extract on Sleep Quality, Relaxation, and GABA/Seroto." *Antioxidants (Basel, Switzerland)*, 2024. PMID: [38929096](https://pubmed.ncbi.nlm.nih.gov/38929096/)
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  <img src="" alt="Dose-response data from the valerian extract murine study illustrate the relationship between extract concentration and sleep-related outcomes. The graded response pattern supports a pharmacological mechanism involving GABA and serotonin receptor pathways." />
  <figcaption>Figure 26. Dose-response data from the valerian extract murine study illustrate the relationship between extract concentration and sleep-related outcomes. The graded response pattern supports a pharmacological mechanism involving GABA and serotonin receptor pathways.<br>  Source: Kazim Sahin et al. "Impact of a Novel Valerian Extract on Sleep Quality, Relaxation, and GABA/Seroto." <em>Antioxidants (Basel, Switzerland)</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/38929096/">38929096</a></figcaption>
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