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L-Theanine per Sleep-Related Cognitive Impairment

C

Research suggests L-theanine supports sleep quality without sedation and may improve next-day cognitive performance through enhanced sleep architecture.

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In sintesi

Research suggests L-theanine supports sleep quality without sedation and may improve next-day cognitive performance through enhanced sleep architecture.

Key Study Findings

Randomized Controlled Trial 4.3 weeks Single-blind
Assessing brain function in stressed healthy individuals following the use of a combination of green …
Dose: None vs: placebo Outcome: Brain response to stress and quality of life Effetto: None p = 0.001

Popolazione: Chronically stressed but healthy subjects

Randomized Controlled Trial n=46 10 weeks Double-blind
L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
Dose: 450-900 mg L-theanine daily vs: Placebo Effetto: None p=0.73 (anxiety), p=0.35 (inso
Controlled Clinical Trial n=20 8 weeks Open-label
Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study.
Dose: 250 mg/day vs: Placebo Outcome: HAMD-21 depression score, cognitive function Effetto: None pp0.007

Popolazione: Patients with major depressive disorder

Key Statistics

6

Studi

400

Partecipanti

Positive

C

Grado

Referenced Papers

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

general:
100-200 mg/day
withcaffeine:
200 mg L-theanine + 100 mg caffeine

Limite massimo: 900 mg/day (no adverse effects observed in studies)

Dosaggi studiati nella ricerca

Dosaggio Durata Effetto N
None 4.3 weeks Positive --
450-900 mg L-theanine daily 10 weeks Neutral 46
250 mg/day 8 weeks Positive 20

Momento migliore per l'assunzione: Morning or as needed; rapid onset (30-60 minutes)

Safety & Side Effects

Effetti collaterali segnalati

  • Generally very well-tolerated
  • Mild drowsiness in sensitive individuals
  • Mild headache (rare)

Interazioni note

  • Antihypertensive drugs (may enhance blood pressure lowering)
  • Stimulant medications (counteracts some stimulant side effects)
  • Sedative medications (additive calming effects)

Livello di assunzione massimo tollerabile: 900 mg/day (no adverse effects observed in studies)

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does L-Theanine help with Sleep-Related Cognitive Impairment?
Based on 6 studies with 400 participants, there is limited but promising evidence that L-Theanine may support Sleep-Related Cognitive Impairment management. Our evidence grade is C (Some Evidence).
How much L-Theanine should I take for Sleep-Related Cognitive Impairment?
Studies have used various dosages. A commonly studied range is 100-200 mg/day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of L-Theanine?
Reported side effects may include Generally very well-tolerated, Mild drowsiness in sensitive individuals, Mild headache (rare). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for L-Theanine and Sleep-Related Cognitive Impairment?
We rate the evidence as Grade C (Some Evidence). This rating is based on 6 peer-reviewed studies with 400 total participants. The overall direction of effect is positive.

Related Evidence

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.