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Creatine per Sleep-Related Cognitive Impairment

C Evidenze Evidenza limitata da studi di piccole dimensioni, ma esistono alcuni segnali positivi.

A single-dose study showed creatine improved cognitive performance during sleep deprivation through enhanced brain ATP availability, supporting cognitive function under sleep-restricted conditions.

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In sintesi

            
            
A single-dose study showed creatine improved cognitive performance during sleep deprivation through enhanced brain ATP availability, supporting cognitive function under sleep-restricted conditions.

            
            
        

    










    

  
Key Study Findings





    

        
        

            

                
                    Systematic Review
                
                
                
                
            

            
                Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
            
            

                
                Dose: None
                
                
                vs: None
                
                
                Outcome: Bone, muscle, and cognitive health in elderly
                
                
                Effetto: None
                
                
                None
                
            

            
            
Popolazione: Older adults

            
        

        
    







    
    

        
        

            

  
Key Statistics





            


    

        
4

        
Studi

    

    

        
250

        
Partecipanti

    

    

        
            
            ↑
            
        
        
Positive

    

    

        C

        
Grado

    




        


        
        
        

            

  
Referenced Papers





            

                
                

                    

                        
                            Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
                        
                        
                            
                                Review
                            
                            
                            
                        
                    

                    

                        The journal of …
                        2017
                        
                        75 citazioni
                        
                    

                

                
            

        

        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Dosaggi di uso comune

                

                    
                    

                        
general:

                        
3-5 g/day creatine monohydrate

                    

                    
                    

                        
cognitivesupport:

                        
5 g/day

                    

                    
                

                
                

                    Limite massimo: 5 g/day considered safe for long-term use (ISSN position)
                

                
            

            

            
            

                
Dosaggi studiati nella ricerca

                

                    

                        
                            

                                Dosaggio
                                Durata
                                Effetto
                                N
                            

                        
                        
                            
                            

                                None
                                --
                                
                                    
                                    Positive
                                    
                                
                                --
                            

                            
                        
                    

                

            

            

            
            

                Momento migliore per l'assunzione: Any time of day; with or without food
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Effetti collaterali segnalati

                    
    
                        
                        
  • 
                            ⚠
                            Water retention
                        
    • 
                        
                        
  • 
                            ⚠
                            Mild gastrointestinal discomfort
                        
    • 
                        
                        
  • 
                            ⚠
                            Weight gain (water weight)
                        
    • 
                        
                        
  • 
                            ⚠
                            Muscle cramping (rare, dose-dependent)
                        
    • 
                        
                    

                

                

                
                

                    
Interazioni note

                    
    
                        
                        
  • 
                            ●
                            Nephrotoxic drugs (monitor kidney function with concurrent use)
                        
    • 
                        
                        
  • 
                            ●
                            Caffeine (may partially attenuate creatine loading, debated)
                        
    • 
                        
                        
  • 
                            ●
                            NSAIDs (theoretical additive kidney stress at high doses)
                        
    • 
                        
                    

                

                

                
                

                    

                        Livello di assunzione massimo tollerabile: 5 g/day considered safe for long-term use (ISSN position)
                    

                

                
            

            

                Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Creatine help with Sleep-Related Cognitive Impairment?
            
        
        

            Based on 4 studies with 250 participants, there is limited but promising evidence that Creatine may support Sleep-Related Cognitive Impairment management. Our evidence grade is C (Some Evidence).
        

    

    
    

        
            How much Creatine should I take for Sleep-Related Cognitive Impairment?
            
        
        

            Studies have used various dosages. A commonly studied range is 3-5 g/day creatine monohydrate. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Creatine?
            
        
        

            Reported side effects may include Water retention, Mild gastrointestinal discomfort, Weight gain (water weight), Muscle cramping (rare, dose-dependent). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Creatine and Sleep-Related Cognitive Impairment?
            
        
        

            We rate the evidence as Grade C (Some Evidence). This rating is based on 4 peer-reviewed studies with 250 total participants. The overall direction of effect is positive.
        

    

    




        

        

        
        
        

            

  




            

                
                

                    
Altri ingredienti per Sleep-Related Cognitive Impairment

                    

                        
                        
                            Melatonin
                            C

                        
                        
                        
                            Ashwagandha
                            C

                        
                        
                        
                            L-Theanine
                            C

                        
                        
                        
                            Magnesium L-Threonate
                            C

                        
                        
                    

                

                

                
                

                    
Creatine per altre condizioni

                    

                        
                        
                            Mental Fatigue
                            B

                        
                        
                        
                            Memory Loss
                            C

                        
                        
                    

                

                
            

        

        

    


    
    






  
References

  
    
    
    
  1. 
      [1]
      G Iolascon et al..
      J Nutr Health Aging.
      2017.
      Are Dietary Supplements and Nutraceuticals Effective for Musculoskeletal Health and Cognitive Function? A Scoping Review.
      doi:10.1007/s12603-016-0823-x
      PubMed
    
    2. 
    
  















    

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