Skip to main content
BrainCited

Omega-3 Fatty Acids (DHA/EPA) per Cerebrovascular Health

B

DHA supports vascular endothelial function and may help reduce neuroinflammation. In CAD patients, 3.36 g/day supplementation was associated with slowed cognitive aging equivalent to approximately 2.5 years.

<\/script>\n
`; }, get iframeSnippet() { const domain = 'braincited.com'; const params = 'ingredient\u003Domega\u002D3\u002Ddha\u002Depa\u0026condition\u003Dcerebrovascular\u002Dhealth'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style



      
      
    

Widget powered by . Free, no account required.

B

In sintesi

DHA supports vascular endothelial function and may help reduce neuroinflammation. In CAD patients, 3.36 g/day supplementation was associated with slowed cognitive aging equivalent to approximately 2.5 years.

Key Study Findings

Review
The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A …
Dose: None vs: None Outcome: None Effetto: None None

Popolazione: narrative review of ashwagandha clinical trials and basic research (1994-present)

Other 10 weeks
Ginkgo biloba Extract GBE50 ameliorates cerebrovascular dysfunction and cognitive impairment in a mouse model of …
Dose: None vs: Untreated APP/PS1 mice Outcome: Cognitive performance in behavioral tests Effetto: None None

Popolazione: APP/PS1 transgenic Alzheimer's disease mouse model

Review
Herbal Medicines in Autism Spectrum Disorder: Therapeutic Potential, Plant Components, and Dosage Guidelines.
Dose: None vs: None Outcome: ASD symptom management Effetto: None None

Popolazione: Children with autism spectrum disorder

Cohort Study n=215624
Neuroticism, omega-3 fatty acids, and risk of incident dementia.
Dose: None vs: None Outcome: Incident all-cause dementia Effetto: None <0.05 (Bonferroni)

Popolazione: Dementia-free UK Biobank participants aged 40-69

preclinical animal/in vitro study
Ashwagandha (Withania somnifera (L.) dunal) root extract containing withanolide a alleviates depression-like behavior in mice …
Dose: 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL vs: Placebo Effetto: None None
Other 26 weeks
Systems biology modelling based evaluation of omega-3 formulation in managing cardiovascular and cerebrovascular risk.
Dose: EPA 180mg + DHA 120mg vs: Simulated disease population baseline Outcome: Lipid biomarker changes (in silico model) Effetto: 14.7% TG reduction, 22.38% HDL increase None

Popolazione: Simulated CVD disease population (in silico study)

Key Statistics

12

Studi

2000

Partecipanti

Positive

B

Grado

Referenced Papers

Nutrients 2025 2 citazioni
Acta pharmaceutica Sinica. … 2024 33 citazioni
La Revue du … 2024
Nature reviews. Disease … 2021 163 citazioni
The Senior care … 2021 2 citazioni
Journal of ethnopharmacology 2020 85 citazioni
Current neurology and … 2019 11 citazioni
Sleep medicine 2017 95 citazioni
Current treatment options … 2017 56 citazioni
Clinical therapeutics 2016 328 citazioni
Journal of psychosocial … 2011 26 citazioni
Journal of Alzheimer's … 2010 110 citazioni
The Practitioner 2010
The Cochrane database … 2003 263 citazioni
The Medical clinics … 2002 59 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

general:
1,000-2,000 mg combined DHA/EPA per day
cognitivesupport:
1,000-1,700 mg/day (optimal dose-response curve)

Limite massimo: 3,000 mg/day combined DHA/EPA (FDA GRAS)

Dosaggi studiati nella ricerca

Dosaggio Durata Effetto N
None -- Positive --
None 10 weeks Positive --
None -- Positive --
None -- Positive 215624
60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL -- Positive --
EPA 180mg + DHA 120mg 26 weeks Positive --
None -- Mixed --
None -- Mixed --

Momento migliore per l'assunzione: With meals containing fat for better absorption

Safety & Side Effects

Effetti collaterali segnalati

  • Fishy aftertaste or burping
  • Mild gastrointestinal discomfort
  • Potential increased bleeding time at very high doses
  • May lower blood pressure slightly

Interazioni note

  • Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
  • Blood pressure medications (additive hypotensive effect)
  • Orlistat (may reduce omega-3 absorption)

Livello di assunzione massimo tollerabile: 3,000 mg/day combined DHA/EPA (FDA GRAS)

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Omega-3 Fatty Acids (DHA/EPA) help with Cerebrovascular Health?
Based on 12 studies with 2,000 participants, there is moderate evidence from clinical studies that Omega-3 Fatty Acids (DHA/EPA) may support Cerebrovascular Health management. Our evidence grade is B (Good Evidence).
How much Omega-3 Fatty Acids (DHA/EPA) should I take for Cerebrovascular Health?
Studies have used various dosages. A commonly studied range is 1,000-2,000 mg combined DHA/EPA per day. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Omega-3 Fatty Acids (DHA/EPA)?
Reported side effects may include Fishy aftertaste or burping, Mild gastrointestinal discomfort, Potential increased bleeding time at very high doses, May lower blood pressure slightly. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Omega-3 Fatty Acids (DHA/EPA) and Cerebrovascular Health?
We rate the evidence as Grade B (Good Evidence). This rating is based on 12 peer-reviewed studies with 2,000 total participants. The overall direction of effect is positive.

Related Evidence

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.