Omega-3 Fatty Acids (DHA/EPA) 用于 脑血管健康
B 证据 至少一项随机试验支持这一结论,结果基本一致。DHA supports vascular endothelial function and may help reduce neuroinflammation. In CAD patients, 3.36 g/day supplementation was associated with slowed cognitive aging equivalent to approximately 2.5 years.
结论
DHA supports vascular endothelial function and may help reduce neuroinflammation. In CAD patients, 3.36 g/day supplementation was associated with slowed cognitive aging equivalent to approximately 2.5 years.
Key Study Findings
研究人群: narrative review of ashwagandha clinical trials and basic research (1994-present)
研究人群: Simulated CVD disease population (in silico study)
研究人群: None
研究人群: Review of CoQ10 supplementation and cognition
研究人群: APP/PS1 transgenic Alzheimer's disease mouse model
Key Statistics
12
研究数量
2000
受试者
Positive
等级
Referenced Papers
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
常用剂量
- general:
- 1,000-2,000 mg combined DHA/EPA per day
- cognitivesupport:
- 1,000-1,700 mg/day (optimal dose-response curve)
上限: 3,000 mg/day combined DHA/EPA (FDA GRAS)
研究中使用的剂量
| 剂量 | 持续时间 | 效果 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| EPA 180mg + DHA 120mg | 26 weeks | Positive | -- |
| 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL | -- | Positive | -- |
| None | -- | Mixed | -- |
| None | -- | Mixed | -- |
| None | 10 weeks | Positive | -- |
| None | -- | Positive | -- |
| None | -- | Positive | 215624 |
最佳服用时间: With meals containing fat for better absorption
Safety & Side Effects
已报告的副作用
- ⚠ Fishy aftertaste or burping
- ⚠ Mild gastrointestinal discomfort
- ⚠ Potential increased bleeding time at very high doses
- ⚠ May lower blood pressure slightly
已知相互作用
- ● Anticoagulants and antiplatelet drugs (may increase bleeding risk at high doses)
- ● Blood pressure medications (additive hypotensive effect)
- ● Orlistat (may reduce omega-3 absorption)
可耐受最高摄入量: 3,000 mg/day combined DHA/EPA (FDA GRAS)
在开始服用任何补充剂之前,请务必咨询您的医疗保健提供者。
Frequently Asked Questions
Does Omega-3 Fatty Acids (DHA/EPA) help with 脑血管健康?
How much Omega-3 Fatty Acids (DHA/EPA) should I take for 脑血管健康?
Are there side effects of Omega-3 Fatty Acids (DHA/EPA)?
How strong is the evidence for Omega-3 Fatty Acids (DHA/EPA) and 脑血管健康?
Related Evidence
其他成分用于 脑血管健康
Omega-3 Fatty Acids (DHA/EPA) 用于其他健康状况
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