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BrainCited

Omega-3 Fatty Acids (DHA/EPA) 図

21 査読済み研究からの図表

すべて Vitamin E Green Tea Extract (EGCG) Citicoline Folate Zinc Bacopa monnieri Omega-3 Fatty Acids (DHA/EPA) Alpha-Lipoic Acid Creatine Resveratrol Vitamin D L-Theanine Vitamin B12 Ginkgo biloba Lutein & Zeaxanthin Melatonin Rhodiola rosea Panax Ginseng Phosphatidylserine Taurine Curcumin Uridine Monophosphate
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Figure 1. Overview of the key anti-inflammatory actions of EPA and DHA. DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; NFκB, nuclear factor kappa-light-chain-enhancer of activated B cells; PPAR, peroxisome proliferator activated receptor; TLR, toll
Figure 5 Diagram

Key anti-inflammatory actions of EPA and DHA include suppression of NF-kB activation, reduction of pro-inflammatory eicosanoid production, inhibition of NLRP3 inflammasome activation, and promotion of regulatory T-cell differentiation through PPAR-gamma signaling.

Expert Opinion on Benefits of Long-Chain Omega-3 Fatty Acids (DHA and EPA) …

Figure 5
Figure 5 Diagram

Neuroprotective and anti-fatigue properties of cordycepin have been demonstrated in preclinical models. This figure highlights cordycepin's potential benefits for neurological health and physical performance.

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic …

Figure 6
Figure 6 Diagram

Cordycepin modulates immune responses through effects on macrophage activation and cytokine production. This figure presents immunomodulatory data from in vitro and in vivo studies of cordycepin treatment.

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic …

Figure 7
Figure 7 Diagram

Anti-microbial and anti-viral activities of cordycepin complement its anti-inflammatory properties. This figure summarizes evidence for cordycepin's broad-spectrum antimicrobial potential.

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic …

Figure 9
Figure 9 Diagram

Preclinical evidence supports cordycepin's hepatoprotective and nephroprotective properties. This figure presents data on cordycepin's organ-protective effects in various disease models.

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic …

Figure 4. (A) Possible mechanism of cordycepin for its anti-diabetic activity (B) Possible mechanism of cordycepin in regulation of fat metabolism in hyperlipidemia [47].
Figure 10 Diagram

Cordycepin may exert anti-diabetic effects through regulation of glucose metabolism and insulin sensitivity. Panel A illustrates the proposed mechanism for anti-diabetic activity, while Panel B depicts cordycepin's role in fat metabolism regulation in hyperlipidemia.

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic …

Figure 1
Figure 1 Diagram

Alzheimer's disease involves a complex pathological cascade initially triggered by amyloid-beta accumulation or aberrant APP processing. This figure argues for pleiotropic interventions that simultaneously target multiple pathological mechanisms rather than single molecular targets.

Why pleiotropic interventions are needed for Alzheimer's disease.

Figure 1. Organs and functions modulated by omega-3 PUFAs in older adults.
Figure 1 Diagram

Target organs and physiological functions modulated by omega-3 polyunsaturated fatty acids in older adults are mapped, illustrating the widespread systemic benefits of EPA and DHA supplementation across cardiovascular, neurological, and musculoskeletal systems.

The role for dietary omega-3 fatty acids supplementation in older adults.

Fig. 1. The underlying mechanism of depression. Brain insulin resistance develops due to the failure of brain cells to respond to insulin activity. The hippocampus, hypothalamus, and cortex regions of the central nervous system regulate insulin levels in
Figure 3 Diagram

Brain insulin resistance mechanisms underlying depression are depicted, showing how HPA axis dysregulation, reduced anterior cingulate cortex volume, and impaired hippocampal function contribute to the condition.

A review on linking stress, depression, and insulin resistance via low-grade chronic …

Fig. 2. Obesity, diabetes, and metabolic syndrome are metabolic diseases that coexist with depression-Created with BioRender.com.
Figure 4 Diagram

Obesity, diabetes, and metabolic syndrome are illustrated as metabolic diseases that commonly coexist with depression, highlighting their shared pathophysiological mechanisms through chronic low-grade inflammation.

A review on linking stress, depression, and insulin resistance via low-grade chronic …

Figure 5
Figure 5 Diagram

Molecular pathways connecting stress-induced inflammation to insulin resistance are detailed, tracing how inflammatory signaling cascades impair insulin receptor substrate phosphorylation.

A review on linking stress, depression, and insulin resistance via low-grade chronic …

Figure 6
Figure 6 Diagram

Bidirectional relationships between depression and metabolic disturbances are outlined, showing how each condition exacerbates the other through shared inflammatory and neuroendocrine mechanisms.

A review on linking stress, depression, and insulin resistance via low-grade chronic …

Fig. 5. Treatment option for major depressive disorders-Created with BioRender.com.
Figure 7 Diagram

Treatment options for major depressive disorders are presented, including pharmacological, psychological, and lifestyle interventions that address the inflammatory-metabolic axis.

A review on linking stress, depression, and insulin resistance via low-grade chronic …

Fig. 6. A schematic representation of the factors affecting metabolic syndrome and the corresponding dietary and lifestyle changes for the alleviating the same.
Figure 8 Diagram

A schematic representation maps the factors contributing to metabolic syndrome alongside corresponding dietary and lifestyle modifications that may alleviate these conditions, integrating evidence on stress management and anti-inflammatory nutrition.

A review on linking stress, depression, and insulin resistance via low-grade chronic …

Figure 1
Figure 1 Diagram

Major pharmacotherapeutic targets in Alzheimer's disease are mapped, including amyloid-beta aggregation, tau hyperphosphorylation, neuroinflammation, and cholinergic dysfunction as key intervention points.

Review of Pharmacotherapeutic Targets in Alzheimer's Disease and Its Management Using Traditional …

Figure 2
Figure 2 Diagram

The amyloid cascade hypothesis and its therapeutic targets are illustrated, showing how beta-secretase and gamma-secretase inhibitors, along with anti-amyloid antibodies, aim to reduce pathological plaque formation.

Review of Pharmacotherapeutic Targets in Alzheimer's Disease and Its Management Using Traditional …

Figure 3
Figure 3 Diagram

Tau protein pathology and potential therapeutic interventions are depicted, including kinase inhibitors and immunotherapy approaches targeting neurofibrillary tangle formation in Alzheimer's disease.

Review of Pharmacotherapeutic Targets in Alzheimer's Disease and Its Management Using Traditional …

Figure 4
Figure 4 Diagram

Neuroinflammatory pathways in Alzheimer's disease and anti-inflammatory therapeutic targets are outlined, showing microglial activation, cytokine cascades, and potential points of pharmacological intervention.

Review of Pharmacotherapeutic Targets in Alzheimer's Disease and Its Management Using Traditional …

Figure 5
Figure 5 Diagram

Traditional medicinal plants investigated for Alzheimer's management are catalogued with their bioactive compounds and proposed neuroprotective mechanisms, including antioxidant and anti-inflammatory activities.

Review of Pharmacotherapeutic Targets in Alzheimer's Disease and Its Management Using Traditional …

Figure 6
Figure 6 Diagram

Cholinergic system dysfunction in Alzheimer's disease and current cholinesterase inhibitor therapies are illustrated, showing how acetylcholine deficiency contributes to cognitive decline.

Review of Pharmacotherapeutic Targets in Alzheimer's Disease and Its Management Using Traditional …

Fig 1. The possible mechanisms of action of compound nutrients. Ach: acetylcholine; cAMP: Cycilic adenosine monophospate; APP: amyloid precursor protein-presenilin; Aβ: anti-β-amyloid; GSH-PX: glutathione peroxidase; SOD: superoxide dismutase; TChE: total
Figure 4 Diagram

A schematic diagram illustrates the proposed mechanisms by which the compound nutrient mixture may protect against Alzheimer's pathology, including acetylcholine and cAMP signaling.

Protective Effects of Dietary Supplementation with a Combination of Nutrients in a …