What is the recommended dosage for Alpha-GPC?

General: 300-600 mg/day; Cognitive Support: 600-1,200 mg/day

What are the side effects of Alpha-GPC?

Potential side effects include: Headache, Insomnia, Dizziness, Gastrointestinal discomfort, Fishy body odor at high doses (TMAO conversion).

Alpha-GPC (alpha-glycerophosphocholine) is a choline-containing compound that serves as a precursor to the neurotransmitter acetylcholine. It is one of the most bioavailable forms of choline and has been studied for its potential role in supporting memory and cognitive function.

What dosage of Alpha-GPC has been used in studies?

Clinical studies have used doses ranging from 300 mg to 1,200 mg per day. A common dosage in cognitive research is 400 mg taken three times daily (1,200 mg total). Consult your healthcare provider for appropriate dosing.

What are the potential side effects of Alpha-GPC?

Alpha-GPC is generally well tolerated. Some people may experience headache, heartburn, insomnia, or dizziness. It may interact with anticholinergic medications. Consult your healthcare provider before taking Alpha-GPC, especially if you are on prescription medications.

Alpha-GPC
Alpha-GPC

choline_source

別名: Alpha-Glycerylphosphorylcholine, L-Alpha Glycerylphosphorylcholine, Choline Alfoscerate

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About

Alpha-GPC is a highly bioavailable choline source that crosses the blood-brain barrier to serve as a precursor for acetylcholine, the primary neurotransmitter for learning and memory. Clinical studies in elderly patients show improvements in cognitive function scores, and it is used as a prescription drug in several European countries.

How It Works

Provides highly bioavailable choline that crosses the blood-brain barrier; serves as a precursor to acetylcholine, the primary neurotransmitter for learning and memory; promotes neural tissue health and enhances neuronal communication.

Evidence For Conditions

症状・状態	グレード	研究数	参加者数
Neurotransmitter Imbalance	B	10	800	詳細を見る →
Age-Related Cognitive Decline	C	8	600	詳細を見る →

Side Effects

Headache
Insomnia
Dizziness
Gastrointestinal discomfort
Fishy body odor at high doses (TMAO conversion)

Drug & Supplement Interactions

Anticholinergic medications (opposes Alpha-GPC effects)
Cholinesterase inhibitors (additive cholinergic effects)
Scopolamine (opposes cholinergic effects)

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Related Ingredients

Choline Bitartrate

基本情報

用量: General: 300-600 mg/day; Cognitive_Support: 600-1,200 mg/day
剤形: capsule powder liquid
天然の供給源: Trace amounts in dairy, organ meats, and soy, Concentrated form extracted from soy lecithin
上限量: Not established; well-tolerated up to 1,200 mg/day
推奨摂取タイミング: Morning or split dose; with or without food

エビデンスの要約

Neurotransmitter Imbalance B

Age-Related Cognitive Decline C

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。