Ashwagandha 관련 스트레스 유발 인지 저하
B 근거 적어도 하나의 무작위 시험이 이를 지지하며, 대체로 일관된 결과를 보입니다.The most scientifically supported adaptogen for stress-related cognitive outcomes. A double-blind RCT found 240 mg/day for 60 days significantly reduced anxiety with moderate improvements in attention and executive function.
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B
결론
The most scientifically supported adaptogen for stress-related cognitive outcomes. A double-blind RCT found 240 mg/day for 60 days significantly reduced anxiety with moderate improvements in attention and executive function.
Key Study Findings
Review
The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A …
Dose: None
vs: None
Outcome: None
효과: None
None
대상 집단: narrative review of ashwagandha clinical trials and basic research (1994-present)
preclinical animal/in vitro study
Ashwagandha (Withania somnifera (L.) dunal) root extract containing withanolide a alleviates depression-like behavior in mice …
Dose: 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL
vs: Placebo
효과: None
None
animal_study
Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in …
Dose: 10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden)
vs: Placebo
효과: At 50 mg/kg: 34% decrease in sleep onset time (p<0.0001); 47% increase in sleep duration (p<0.0001);
<0.0001
In Vitro
Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of …
Dose: ASH root extract 200 mg/kg and 400 mg/kg for 29 days (rat model)
vs: Placebo
효과: ASH improved locomotor and cognitive deficits, serum hepatotoxicity indices, oxidative stress marker
Key Statistics
14
연구
1200
참여자
↑
Positive
B
등급
Referenced Papers
Nutrients
2026
Journal of ethnopharmacology
2025
9 인용
Preventive nutrition and …
2022
18 인용
Journal of ethnopharmacology
2021
69 인용
Journal of ethnopharmacology
2020
85 인용
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
일반적으로 사용되는 용량
- general:
- 300-600 mg/day of root extract (KSM-66 or Sensoril)
- cognitivesupport:
- 600 mg/day
상한량: Not established; well-tolerated up to 1,250 mg/day
연구에서 사용된 용량
| 용량 | 기간 | 효과 | N |
|---|---|---|---|
| None | -- | Positive | -- |
| 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL | -- | Positive | -- |
| 10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) | -- | Positive | -- |
| ASH root extract 200 mg/kg and 400 mg/kg for 29 days (rat model) | -- | Positive | -- |
권장 복용 시간: With meals; morning or evening depending on individual response
Safety & Side Effects
보고된 부작용
- ⚠ Drowsiness
- ⚠ Gastrointestinal discomfort
- ⚠ Rare: liver injury (with contaminated or high-dose products)
- ⚠ Thyroid hormone elevation (may affect thyroid medications)
알려진 상호작용
- ● Thyroid medications (may increase thyroid hormone levels)
- ● Sedative medications (additive CNS depression)
- ● Immunosuppressants (may stimulate immune activity)
- ● Diabetes medications (may lower blood sugar)
일일 최대 섭취 허용량: Not established; well-tolerated up to 1,250 mg/day
건강기능식품을 복용하기 전에 반드시 의료 전문가와 상담하십시오.
Frequently Asked Questions
Does Ashwagandha help with 스트레스 유발 인지 저하?
Based on 14 studies with 1,200 participants, there is moderate evidence from clinical studies that Ashwagandha may support 스트레스 유발 인지 저하 management. Our evidence grade is B (Good Evidence).
How much Ashwagandha should I take for 스트레스 유발 인지 저하?
Studies have used various dosages. A commonly studied range is 300-600 mg/day of root extract (KSM-66 or Sensoril). Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, Gastrointestinal discomfort, Rare: liver injury (with contaminated or high-dose products), Thyroid hormone elevation (may affect thyroid medications). Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and 스트레스 유발 인지 저하?
We rate the evidence as Grade B (Good Evidence). This rating is based on 14 peer-reviewed studies with 1,200 total participants. The overall direction of effect is positive.
Related Evidence
관련 다른 성분: 스트레스 유발 인지 저하
Ashwagandha 다른 건강 상태에 대한 근거
References
- [1] Kaj Winther. Nutrients. 2026. The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A Review. doi:10.3390/nu18050871 PubMed
- [2] Hyeongyeong Kim et al.. J Ethnopharmacol. 2025. Ashwagandha (Withania somnifera (L.) dunal) root extract containing withanolide a alleviates depression-like behavior in mice by enhancing the brain-derived neurotrophic … doi:10.1016/j.jep.2024.119224 PubMed
- [3] Sindgi Vasudeva Murthy et al.. Prev Nutr Food Sci. 2022. Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in In Vitro - In Vivo … doi:10.3746/pnf.2022.27.1.108 PubMed
- [4] Heba M A Khalil et al.. J Ethnopharmacol. 2021. Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of hepatic encephalopathy via induction of … doi:10.1016/j.jep.2021.114141 PubMed
- [5] Nawab John Dar et al.. J Ethnopharmacol. 2020. Neurodegenerative diseases and Withania somnifera (L.): An update. doi:10.1016/j.jep.2020.112769 PubMed
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